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| ITP患者骨髓巨核细胞和血小板参数的临床分析 | |
| 引用本文： | 刘艳奎,朴美花,金春岩,崔海霞,崔海,金京子.ITP患者骨髓巨核细胞和血小板参数的临床分析[J].现代预防医学,2010,37(6). |
| 作者姓名： | 刘艳奎 朴美花 金春岩 崔海霞 崔海 金京子 |
| 作者单位： | 1. 吉林省延吉市延边大学医院检验科,延吉,133000 2. 延边妇婴医院 3. 延吉市二院 |
| 摘 要： | 目的]探讨特发性血小板减少性紫癜(ITP)患者骨髓巨核细胞和血小板4项参数的变化及临床意义。方法]分析经我院确治的99例ITP患者骨髓巨核细胞和血小板数(Plt)、血小板平均体积(MPV)、血小板平均分布宽度(PDW)、大血小板比率(P-LCR)的关系及比较治疗前后血小板4项参数变化。结果]①骨髓巨核细胞数和Plt没有相关性,但颗粒型、产板型巨核细胞和Plt有一定相关性(P﹤0.01)。②Plt与MPV呈负相关(P﹤0.01);MPV与PDW、P-LCR,PDW与P-LCR呈正相关(P﹤0.05)。③ITP患者治疗前Plt明显低于对照组,而MPV、PDW、P-LCR明显高于对照组,差异有统计学意义(P﹤0.001);治疗后Plt上升MPV、PDW、P-LCR下降与治疗前比较差异有统计学意义(P﹤0.001)。结论]观察血小板参数对骨髓巨核细胞产血小板功能及病情判断、疗效观察有重要意义。 |
| 关 键 词： | 特发性血小板减少性紫癜 血小板参数 巨核细胞 |
CLINICAL ANALYSIS OF BONE MARROW MEGAKARYOCYTE AND PLATELET PARAMETER WITH IDIOPATHIC THROMBOCYTOPENIC PURPURA |
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| LIU Yan-kui,PIAO Mei-hua,JIN Chun -yan,et al..CLINICAL ANALYSIS OF BONE MARROW MEGAKARYOCYTE AND PLATELET PARAMETER WITH IDIOPATHIC THROMBOCYTOPENIC PURPURA[J].Modern Preventive Medicine,2010,37(6). | |
| Authors: | LIU Yan-kui PIAO Mei-hua JIN Chun -yan |
| Institution: | LIU Yan-kui,PIAO Mei-hua,JIN Chun -yan,et al. ( Department of Laboratory Medicine,College Medicine,Yanbian University,Yanji 133000,China) |
| Abstract: | Objective] To study the clinical significance of bone marrow megalokaryocyte and four parameters of platelet changes in idiopathic thrombocytopenic purpura (ITP). Methods] The platelet total (PLT), mean platelet volume (MPV), platelet distribution width (PDW), platelet larger cell ratio (P-LCR) and bone marrow megalokaryocyte were detected in 99 cases of ITP before and after treatment. Results] (1) There was no correlation between bone marrow megakaryocyte and platelet, but the granular type and the plat... |
| Keywords: | Idiopathic thrombocytopenic purpura (ITP) Platelet parameter Megakaryocyte |
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