某“三甲”医院2010-2012年H2受体拮抗药和质子泵抑制剂应用分析

目的:评价某"三甲"医院抑酸药的应用情况。方法:对2010-2012年该院H2受体拮抗药和质子泵抑制剂这两类抑酸药的销售金额、用量、用药频度(DDDs)等进行统计、分析。结果:2010-2012年,该院质子泵抑制剂的销售金额始终占抑酸药的99%以上,且金额逐年上升;H2受体拮抗药的销售金额只占1%以下,且构成比逐年降低。泮托拉唑胶囊和奥美拉唑胶囊的用量3年来一直居第1、2位,两者的排序比均大于3;注射用泮托拉唑在静脉用药中的用量最大,排序比为0.33。结论:质子泵抑制剂在该院抑酸药的应用中占绝对主导地位,使用数量及金额逐年增加,但仍存在一些不合理的用药现象。

Analysis of the Application of Acid-Suppressing Drugs H2 Receptor Antagonists and Proton Pump Inhibitors in a Third-grade Class-A Hospital from 2010 to 2012

OBJECTIVE： To evaluate the application of acid-suppressing drugs in a third-grade class-A hospital. METHODS： The utilization of acid-suppressing drugs as H2 receptor antagonists and proton pump inhibitors in the hospital from 2010 to 2012 were statistically analyzed in respects of consumption sum, amount and DDDs. RESULTS ： Consumption sum of proton pump inhibitors always accounted for over 99% in acid-suppressing drugs, increasing year by year; that of H2 receptor antagonists occupied below 1%, and constituent ratio of them was decreased year by year. Pantoprazole and omeprazole took up the front 2 places in the list of consumption amount throughout three years with sort ratio〉 3. The consumption amount of Pantoprazole for injection was the largest among the intravenous drugs with sort ratio of 0.33. CONCLUSIONS ： Although proton pump inhibitors became the mainstream acid-suppressing drugs in the hospital and the amount and consumption sum of them were increased year by year, there were some irrational drug use.