| 硫酸镁对轻度子痫前期患者血中SOD、MDA、NO、 ET、TXA2、PGI2的影响 |
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| 引用本文： | 李维枢,余琳,陈敦金.硫酸镁对轻度子痫前期患者血中SOD、MDA、NO、 ET、TXA2、PGI2的影响[J].热带医学杂志,2005,5(5):701-702. |
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| 作者姓名： | 李维枢 余琳 陈敦金 |
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| 作者单位： | 广州市第二人民医院,广州市重症孕产妇救治中心,广州,510150;广州市第二人民医院,广州市重症孕产妇救治中心,广州,510150;广州市第二人民医院,广州市重症孕产妇救治中心,广州,510150 |
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| 摘 要： | 目的 探讨硫酸镁对轻度子痫前期患者血中超氧化物歧化酶（SOD）、丙二醛（MDA）、一氧化氮（NO）、内皮素（ET）、血栓素A2（TXA2）、前列环I2（PGI2）的影响。方法 硫酸镁治疗中度轻度子痫前期患者75例，观察患者血中治疗前后的SOD、MDA、NO、ET、TXA2、PGI2、平均动脉压的变化情况。结果治疗后患者血中SOD、NO、PGI2、ET、MDA、TXA2较治疗前比较有显著改善（P均〈0．05），治疗前后患者平均动脉压变化无差异（P均〉0．05）。结论 硫酸镁治疗对轻度子痫前期患者SOD、MDA、NO、ET、TXA2、PGI2有影响，但不影响患者平均动脉压。
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| 关 键 词： | 子痫前期 硫酸镁 血管 |
| 文章编号： | 1672-3619（2005）05-0701-02 |
| 收稿时间： | 2005-03-03 |
| 修稿时间： | 2005-04-25 |
Effect of Magnesium Sulfate on Plasma SOD, NO, PGI2, MDA, ET and TXA2 Levels in Patients with Preeclampsia |
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| LI Wei-shu,YU Lin,CHEN Dun-jin.Effect of Magnesium Sulfate on Plasma SOD, NO, PGI2, MDA, ET and TXA2 Levels in Patients with Preeclampsia[J].Journal Of Tropical Medicine,2005,5(5):701-702. |
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| Authors: | LI Wei-shu YU Lin CHEN Dun-jin |
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| Abstract: | Objective To study the effect of magnesium sulfate treatment on circulating concentrations of SOD, MDA, NO, ET, TXA2 and PGI2 in women with preeclampsia. Methods 75 women with mild preeclampsia were treated with magnesium sulfate. The circulating concentrations of SOD, MDA, NO, ET, TXA2, PGI2 and blood pressure were measured during the treatment. Results There was a significant differences of SOD, MDA, NO, ET, TXA2, and PGI2 levels in maternal blood circulation between pre-treatment and post-treatment(P<0.05), while no difference was found in blood pressure drop (P>0.05). Conclusion Our study shows that magnesium sulfate treatment can well balance circulating levels of SOD, MDA, NO, ET, TXA2, and PGI2 in women with preeclampsia. |
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| Keywords: | preeclampsia magnesium sulfate vascular |
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