舒芬太尼复合罗哌卡因腰硬联合麻醉在子宫切除术中的应用

目的探讨罗哌卡因复合小剂量舒芬太尼腰硬联合麻醉在子宫切除术中的效果。方法选择拟行经腹子宫切除术患者60例,ASAⅠ～Ⅱ级,年龄35～69岁,体重46～80kg。随机分为三组,对照组(R)注射1%罗哌卡因2mL+10%葡萄糖1mL,实验1组(S1)组注射1%罗哌卡因2mL+10%葡萄糖1mL+舒芬太尼5μg(0.1mL),实验2组(S2)组注射1%罗哌卡因1.5mL+10%葡萄糖1mL+舒芬太尼5μg(0.1mL)。蛛网膜穿刺成功后,混合液以0.5mL/s的速率注入蛛网膜下腔。记录麻醉前后血流动力学变化,感觉阻滞,运动阻滞,总镇痛时间,肌松程度等指标。结果S1组麻醉起效时间,达T10平面时间和最高平面时间短于S2、R组(P0.01),回复至T10时间和镇痛时间长于S2、R组(P0.01),三组间血流动力学和运动阻滞时间比较差异无统计学意义(P0.05)。结论罗哌卡因复合舒芬太尼后麻醉起效时间缩短,镇痛时间延长,并能减少罗哌卡因的用量。

Sufentanil combined with ropivacaine for spinal-epidural anesthesia during hysterectomy

【Objective】 To investigate the effect of ropivacaine combined with low-dose sufentanil for spinal-epidural anesthesia in hysterectomy.【Methods】 sixty patient s（ASA classⅠor Ⅱ,ages 35 to 69 years old,weighing 46 ~ 80kg）undergoing abdominal hysterectomy were randomLy divided into three groups with 20 cases control group（R） injection of 1% ropivacaine 2mL ＋10% glucose,1mL,experimental group 1（S1） group received 1% ropivacaine 2mL ＋10% glucose 1mL ＋ sufentanil 5μg（0.1mL）,experimental group 2（S2） received 1% ropivacaine 1.5mL ＋10% glucose 1mL ＋ sufentanil 5μg（0.1mL）. After the success of Arachnoid puncture,the mixture to 0.5mL / s of rate was injected.Hemodynamic changes before and after anesthesia,sensory block,motor block,total analgesia time,indicators of the degree of muscle relaxationwere recorded.【Results】 Compaired with S2,R group,the onset time of anesthesia,reaching to the T10 plane of time,and the highest plane of time were shorter（P 0.01）,the time of returning to the T10 and analgesia was longer than S2,R group（P 0.01）,among the three groups hemodynamics and motor blockade were no significant difference（P 0.05）.【Conclusion】 shorting time of the onset of anesthesia,extending time of analgesia,and reducing the amount of ropivacaine.is in ：Ropivacaine combined with sufentanil.