Nucleic Acids and Cytological Changes in the Thyroid Gland after Thiouracil.l |
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| Authors: | JAROSLAV R̂CER̂ÂBEK EMMY R̂CER̂CR̂BEK |
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| Affiliation: | Institute for Research in Organic Chemistry and the Vitamin Institute, Stockholms Hogskola. |
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| Abstract: | 1) By the action of thiouracil the follicular cell is not brought into the state of physiological inactivity and it shows signs of apparent secretion which differ however in details remarkably from the effective secretion stage. 2.) The quantity of follicular cells in mitosis is temporarily increased to the multiple. This disturbance is the result of the inhibition of caryokinesis in the stage of metaphase. 3) The absolute quantities of ribonucleic and of desoxyribonu-cleic acid are considerably reduced. 4) The ratio KNA/DNA shows a decrease to a fractional part of the normal value, according to the increase of the cell mass. |
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