免疫比浊法和快速ELISA法定量检测D-二聚体的相关性探讨

目的探讨免疫比浊法(LIATESTD-D)和快速ELISA法(VIDAS D-D)两种D-二聚体定量方法的相关性。方法分别用LIATESTD-D和VIDAS D-D两种方法对108份健康体检及住院患者标本进行D-二聚体定量检测。对检测的结果作统计学分析。结果当D-二聚体检测值在500~1000万g/ml之间时r2=0.9947,两种方法之间有良好的相关性。当D-二聚体检测值<500 ng/ml和>1000 ng/ml时,相关系数分别为r1=0.9697和r3=0.9538,两种方法之间的相关性不理想。结论两种方法各有优势,实验室可以根据实际情况采取不同的方法检测。

Study on correlation of two kinds of quantitative D-dimer method,liatest D-dimer assay and vidas D-dimer assay

Objective To correlate and compare the two quantitative analytical methods,Stago Liatest D-dimer-assay(LIA) and Biomerieux Vidas D-dimer assay(VIDAS).MethodsTo detect the quantitative D-dimer of 108 peoples which in medical examination or in hospital by two assays,Stago Liatest D-dimer assay(LIA) and Biomerieux Vidas D-dimer assay(VIDAS).ResultsThe correlation of two methods is good when D-dimer is between 500-1000 ng/ml,the correlative coefficient:r2=0.9947.But The correlation of two methods is not ideal when D-dimer is<500 ng/ml and>1000 ng/ml,the correlative coefficient r1=0.9697 and r3=0.9538.ConclusionThe two assays have their own advantage in D-dimer detection.The laboratory should select the fit one according to their demands.