原发性肝癌合并脾亢的介入治疗

目的:探讨肝动脉灌注化疗并栓塞(TACE)结合部分性脾动脉栓塞(PASE)治疗原发性肝癌合并脾功能亢进的应用价值。材料与方法:对36例中晚期肝癌病人在进行肝动脉灌注化疗栓塞的同时进行部分性脾动脉栓塞治疗,观察病人白细胞、血小板计数、肝功能的变化、肿瘤缩小等情况和术后反应,判断治疗效果。结果:所有病人治疗后白细胞和血小板计数升高,肝功能恢复快,术后1个月临床症状改善,肿瘤体积有不同程度缩小,无严重并发症发生。结论:TACE和PASE是治疗原发性肝癌合并脾功能亢进安全、有效的方法。有助于改善患者肝功能,缓减脾功能亢进,促使白细胞、血小板升高,为肝癌介入治疗的顺利进行创造条件。

Interventional Treatment of Primary Hepatic Carcinoma Complicated with Hyperspleism

Purpose:Discussing the value of Transhepatic artery chemo-embolization(TACE) and partial artery spleen embolization in the treatment of primary hepatic carcinoma(PASE) complicated with hypersplenism.Materials and Methods:36 cases of middle-late primary hepatic carcinoma were treated with TACE and PASE.Mean while counts of WBC and PLT,and hepatic function,tumor mass size and reaction after operation were observed to judge the curatve effect.Results:Affter operation,counts of WBC and PLT were increased,hepatic function wse recovered rapidly,clinic symptoms were improved and tumor mass was shrinking after operation for one month for all patients.And there were no severe complications at all.Conclusion:of TACE and PASE are safe and effective therapy to treat primary hepatic carcinoma complicated with hyperspleism.They can improve liver function,decelerate hyperspleism and increased the counts of WBC and PLT to create conditon for interventional treatment of primary hepatic carcinoma.