| 131I治疗对Graves眼病的效果及对细胞因子的影响 |
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| 引用本文： | 方文珠,林敏华,罗章伟,陆进,凌彩霞,廖书鸿. 131I治疗对Graves眼病的效果及对细胞因子的影响[J]. 中国医药导报, 2012, 9(33): 49-51 |
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| 作者姓名： | 方文珠 林敏华 罗章伟 陆进 凌彩霞 廖书鸿 |
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| 作者单位： | 方文珠 (右江民族医学院附属医院核医学科,广西百色,533000) ； 林敏华 (右江民族医学院附属医院核医学科,广西百色,533000) ； 罗章伟 (右江民族医学院附属医院核医学科,广西百色,533000) ； 陆进 (右江民族医学院附属医院核医学科,广西百色,533000) ； 凌彩霞 (右江民族医学院附属医院核医学科,广西百色,533000) ； 廖书鸿 (右江民族医学院附属医院核医学科,广西百色,533000) ； |
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| 基金项目： | 广西壮族自治区卫生厅科研基金 |
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| 摘 要： | 目的探讨131I治疗对Graves眼病（GO）的效果及对细胞因子的影响。方法将100例GO患者进行131I治疗后观察GO的变化,并检测IL-6、IL-8、IL-10水平。结果 GO治愈占32%,改善占50%,无变化占13%,加重占5%,131I治疗后IL-6、IL-8、IL10水平比治疗前明显下降。结论131I治疗能抑制GO患者自身免疫,对GO安全有效。
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| 关 键 词： | Graves眼病 131I治疗 细胞因子 |
Effect of Graves ophthalmopathy patients and cytokine treatment with iodine-131 |
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| FANG Wenzhu,LIN Minhua,LUO ZHangwei LU Jin,LING Caixia,LIAO Shuhong. Effect of Graves ophthalmopathy patients and cytokine treatment with iodine-131[J]. China Medical Herald, 2012, 9(33): 49-51 |
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| Authors: | FANG Wenzhu LIN Minhua LUO ZHangwei LU Jin LING Caixia LIAO Shuhong |
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| Affiliation: | Department of Nuclear Medicine,the Affiliated Hospital of Youjiang Medical College for Nationalities,Guangxi Zhuang Autonomous Region,Baise 533000,China |
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| Abstract: | Objective To study the influence of Graves ophthalmopathy（GO） and cytokine treated with Iodine-131（131I）.Methods 100 patients with GO after treated with 131I to observe GO changes and IL-6,IL-8,IL-10 levels were detected.Results GO cure rate was 32%,improvement was 50%,no change was 13%,increased was 5%,after treated with 131I,IL-6,IL-8,IL-10 levels decreased significantly compared with before treatment.Conclusion 131I therapy can effectively suppress the autoimmunity of patients with GO and is safe to GO. |
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| Keywords: | Graves ophthalmopathy Iodine-131 treatment Cytokine |
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