Rolandic encephalopathy and epilepsia partialis continua following bone marrow transplant |
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Authors: | Antunes N L Boulad F Prasad V Rosenblum M Lis E Souweidane M |
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Affiliation: | Department of Pediatrics, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA. |
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Abstract: | Epilepsia partialis continua (EPC) is a condition defined by prolonged focal myoclonus. Often resistant to therapy, EPC in children is frequently present in Rasmussen encephalitis, a form of chronic encephalitis of uncertain etiology. We discuss a child who developed bilateral EPC 5 months after a bone marrow transplant. Neuroimaging studies showed signal abnormalities on both sensory-motor areas. An extensive search failed to reveal the etiology of the disorder, but treatment with a broad-spectrum anti-viral agent was associated with resolution of the process. An unidentified infectious agent may be responsible for an encephalitis of the motor strip in immunosuppressed patients. |
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