四逆汤治疗冠心病心绞痛的临床研究

目的:观察四逆汤对冠心病心绞痛的临床疗效.方法:将中医辨证为寒凝或阳虚共65例的冠心病心绞痛患者随机分为四逆汤治疗组和消心痛对照组,比较两者在症状、ECG、心肌耗氧、心功能等方面的疗效.结果:在降低心肌耗氧、改善心功能方面,四逆汤疗效优于消心痛;在改善冠心病心绞痛临床症状、ECG、降低心绞痛发作次数、减少硝酸甘油用量等方面与消心痛相似.结论:四逆汤可用于冠心病心绞痛的治疗,对寒凝或阳虚型冠心病心绞痛有确切疗效.

Clinical Study on "Sini" Decoction on Treating Stenocardia for Coronary Heart Disease

Objective: To observe clinical effect of "Sini" decoction on stenocardia for coronary heart disease.Methods: 65 cases of stenocardia for CHD with deficiency of yang or cold syndrome were randomly divided into"Sini" decoction therapeutic group and isosorbide dinitrate controll group. Drug effects of the two groups were compared by clinical symptoms, electrocardiogram(ECG), myocardial oxygen consumption and cardiac function. Results:"Sini" decoction had better effects on reducing myocardial oxygen consumption and improving cardiac function isosorbide dimitrate, and similar to improving clinical symptoms and ECG, decreasing frequency of stenocardia and dose of nitroglycerin on stenocardia for coronary heart disease. Conclusion:"Sini" decoction can treat stenocardia for CHD with deficiency of yang or cold syndrome.