| 胃肠道间质瘤39例临床病理分析 |
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| 引用本文： | 赵再秋,章美珍,翟梅娟,任兴昌. 胃肠道间质瘤39例临床病理分析[J]. 中国肿瘤临床与康复, 2002, 9(6): 94-95 |
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| 作者姓名： | 赵再秋 章美珍 翟梅娟 任兴昌 |
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| 作者单位： | 杭州市萧山区第一医院病理科,浙江,311200 |
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| 摘 要： | 目的 探讨胃肠道间质瘤 (gastrointestinalstromaltumor ,GIST)的临床病理特点及免疫组化表型特征。 方法 对 3 9例GIST进行组织学、免疫组化观察。结果 肿瘤具有梭形和 (或 )上皮样细胞成份 ,间质可有团丝样纤维(SP) ,CD 117表达者 3 5例 (89.7% ) ,CD3 4表达者 2 8例 (71.8% )。结论 GIST可能起源于卡哈尔细胞或向卡哈尔细胞分化 ,组织学上类似于平滑肌肿瘤或神经鞘瘤 ,CD117、CD3 4是较为特异且敏感的标记物。
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| 关 键 词： | 胃肠肿瘤 免疫组织化学 |
| 文章编号： | 1005-8664(2002)06-0094-02 |
| 修稿时间： | 2001-09-23 |
Clinicopathological study on 30 cases of gastrointestinal stromal tumor |
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| ZHAO Zai-qiu,ZHANG Mei zhen,ZHAI Mei juan,et al.. Clinicopathological study on 30 cases of gastrointestinal stromal tumor[J]. Chinese Journal of Clinical Oncology and Rehabilitation, 2002, 9(6): 94-95 |
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| Authors: | ZHAO Zai-qiu ZHANG Mei zhen ZHAI Mei juan et al. |
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| Affiliation: | ZHAO Zai-qiu,ZHANG Mei zhen,ZHAI Mei juan,et al. Department of Pathology,1st Municipal Hospital,Xiaoshan 311200,China |
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| Abstract: | Objective To study the clinicopathological and immunophenotypical features of gastrointestinal stroml tumor(GIST).Methods 39 cases of GIST were studied by light microscopy and immunohistochemical techniques.Results GIST was composed of spindle cells and (or) epithelioid cells.Various sized eosinophilic globules were observed between the tumor cells and were designated as skeinoid fibers.The positive rates by immunohistochemical methods for CD117 and CD34 were 89.7% and 71.8% respectively.Conclusion GIST may be derived from interstitial cell of Cajal or show differentiation toward interstitial cell of Cajal.The histological characters are similar to smooth muscle tumor and schwannoma.CD177 and CD34 are specific and sensitive markers. |
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| Keywords: | gastrointestinal neoplasms immunohistochemistry |
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