非糖尿病尿路感染患者在治疗中监测血糖的价值分析

目的 通过动态监测非糖尿病患者尿路感染治疗前后空腹血糖(Glu)和外周血中白细胞(WBC)变化,了解该类患者Glu升高是异常升高还是急性泌尿系感染的应激反应所致.方法 收集153例确诊尿路感染患者的资料,包括89例血糖正常患者以及64例血糖调节受损(IGR)患者,分别统计入院时、采集尿培养时以及好转出院时的Glu和WBC结果,80例健康体检者作为正常对照.结果 89例血糖正常患者中,46例院内感染患者入院时与出院时以及正常体检人群的Glu和WBC差异无统计学意义(P＞0.05),采集尿培养时的Glu和WBC结果均高于入院以及出院和体检人群(P ＜0.05);43例入院时即尿培养阳性的患者Glu和WBC均高于出院及正常体检人群(P＜0.05);89例患者采集尿培养时的Glu和WBC升高比值成一定的正相关,相关系数r=0.801(P ＜0.05).64例IGR患者中,30例院内感染患者入院时与出院时的Glu和WBC差异无统计学意义(P＞0.05),但Glu高于正常对照组(P＜0.05),采集尿培养时的Glu和WBC结果均高于入院以及出院和体检人群(P＜0.05);34例入院时即尿培养阳性的患者Glu和WBC均高于出院及正常体检人群(P＜0.05);64例患者采集尿培养时的Glu和WBC升高比值成一定的正相关,相关系数r=0.658(P ＜0.05).结论 非糖尿病尿路感染患者Glu升高可能是应激反应所致,Glu检测可作为非糖尿病尿路感染患者监测病情,评估预后的一种方法.

Value of Blood Glucose Monitoring in Non-diabetic Patients with Urinary Tract Infection

Objective To investigate the changes of fasting plasma glucose (Glu) and peripheral white blood cell(WBC) in non-diabetic patients with urinary tract infection(UTI) before and after treatment,and to evaluate whether these patients have elevated Glu or abnormal urinary tract infection reaction.Methods We collected the data of 153 patients diagnosed with UTI,including 89 patients with normal blood glucose and 64 patients with impaired glucose regulation (IGR).The levels of Glu and WBC were detected at the time of hospitalization,urinary culture,and hospital discharge,respectively.80 healthy subjects were included in the control group.Results There were no significant differences of Glu and WBC in 46 subjects among the 89 patients with normal Glu between hospitalization and hospital discharge (P ＞ 0.05).However,results of Glu and WBC at the time of UTI diagnosis were significantly higher than the time of hospitalization and hospital discharge,and were higher than the control group (P ＜ 0.05).The serum Glu and WBC of 43 patients with UTI at hospitalization were higher than the time of hospital discharge and the control group (P ＜ 0.05).Glu and WBC were positively correlated with a coefficient of r =0.801 in 89 cases (P ＜ 0.05).There was no significant difference in Glu and WBC of 30 subjects among the 64 patients between hospitalization and hospital discharge (P ＞ 0.05),but Glu was higher than the control group (P ＜ 0.05).Glu of urinary cultures was collected from 64 IGR patients and WBC were higher than those of hospitalized and discharged patients(P ＜ 0.05).The serum Glu and WBC of 34 patients with UTI among the 64 patients at hospitalization were higher than the hospital discharge and the control group (P ＜ 0.05).Glu and WBC were positively correlated with a coefficient of r =0.658 in 64 cases (P ＜ 0.05).Conclusion Glu abnormal increase may be due to stress,Glu could be used as a test to monitor the UTI condition in non-diabetic patients and evaluate the prognosis of non-diabetic UTI.