| 腹腔感染后抗氧化能力对血浆维生素A、E、C水平的影响 |
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| 引用本文： | 鲍扬,李维勤,黎介寿. 腹腔感染后抗氧化能力对血浆维生素A、E、C水平的影响[J]. 肠外与肠内营养, 2002, 9(3): 129-131 |
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| 作者姓名： | 鲍扬 李维勤 黎介寿 |
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| 作者单位： | 第二军医大学南京临床医学院,南京军区南京总医院,解放军普通外科研究所,江苏南京,210002;第二军医大学南京临床医学院,南京军区南京总医院,解放军普通外科研究所,江苏南京,210002;第二军医大学南京临床医学院,南京军区南京总医院,解放军普通外科研究所,江苏南京,210002 |
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| 基金项目： | 全军“十五”重点科研项目资助 (批准号 :0 1Z 0 11) |
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| 摘 要： | 目的：观察腹腔感染后抗氧化能力对血浆维生素A、E、C水平的影响。方法：采用盲肠结扎加穿孔（CLP）模型，观察腹腔感染后丙二醛（MDA）、还原型谷胱甘肽（GSH）对血浆维生素A、E、C水平的影响。结果：CLP后血浆维生素A、C、E、GSH均明显下降，而血浆MDA显著升高，并发现血浆GSH与维生素A的变化有显著相关性，而血浆MDA与维生素C、E的变化也有显著相关性。结论：腹腔感染后由于机体抗氧化能力的下降而导致维生素A、C、E的大量消耗，可能是造成维生素A、E、C缺乏的重要原因。
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| 关 键 词： | 维生素 感染 抗氧化 |
| 文章编号： | 1007-810X(2002)03-0129-03 |
| 修稿时间： | 2002-04-04 |
The influence of antioxidation on plasma vitamin A,E,C following intraabdominal sepsis in rats |
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| BAO Yang,LI Wei qin,LI Jie shou. The influence of antioxidation on plasma vitamin A,E,C following intraabdominal sepsis in rats[J]. Parenteral & Enteral Nutrition, 2002, 9(3): 129-131 |
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| Authors: | BAO Yang LI Wei qin LI Jie shou |
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| Abstract: | Objectives:To determine the influence of antioxidation on plasma vitamin A,E,C following intraabdominal sepsis in rats. Methods:The model of cecal ligation and puncture(CLP) was used. Plasma vitamin A,E,C,malondialdehyde(MDA) and glutathione(GSH) were measured at 0,1,3,5 day after CLP,and the relation of their linear regression were analysed. Results:Plasma vitamin A,E,C and GSH were decreased and MDA was increased significantly after CLP.Plasma vitamin A was correlated with GSH and vitamin C,E were correlated with MDA significantly. Conclusions:The decreased antioxidation may be the main reason of vitamin A,E,C deficiency after sepsis. |
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| Keywords: | Vitamins Sepsis Antioxidation |
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