| 腹腔感染后抗氧化能力对血浆维生素A、E、C水平的影响 |
| |
| 引用本文： | 鲍扬,李维勤,黎介寿.腹腔感染后抗氧化能力对血浆维生素A、E、C水平的影响[J].肠外与肠内营养,2002,9(3):129-131. |
| |
| 作者姓名： | 鲍扬 李维勤 黎介寿 |
| |
| 作者单位： | 第二军医大学南京临床医学院,南京军区南京总医院,解放军普通外科研究所,江苏南京,210002 |
| |
| 基金项目： | 全军“十五”重点科研项目资助 (批准号 :0 1Z 0 11) |
| |
| 摘 要： | 目的：观察腹腔感染后抗氧化能力对血浆维生素A、E、C水平的影响。方法：采用盲肠结扎加穿孔（CLP）模型，观察腹腔感染后丙二醛（MDA）、还原型谷胱甘肽（GSH）对血浆维生素A、E、C水平的影响。结果：CLP后血浆维生素A、C、E、GSH均明显下降，而血浆MDA显著升高，并发现血浆GSH与维生素A的变化有显著相关性，而血浆MDA与维生素C、E的变化也有显著相关性。结论：腹腔感染后由于机体抗氧化能力的下降而导致维生素A、C、E的大量消耗，可能是造成维生素A、E、C缺乏的重要原因。
|
| 关 键 词： | 腹腔感染 抗氧化能力 血浆 维生素A 维生素C 维生素E |
| 文章编号： | 1007-810X(2002)03-0129-03 |
| 修稿时间： | 2002年4月4日 |
The influence of antioxidation on plasma vitamin A,E,C following intraabdominal sepsis in rats |
| |
| BAO Yang,LI Wei qin,LI Jie shou.The influence of antioxidation on plasma vitamin A,E,C following intraabdominal sepsis in rats[J].Parenteral & Enteral Nutrition,2002,9(3):129-131. |
| |
| Authors: | BAO Yang LI Wei qin LI Jie shou |
| |
| Abstract: | Objectives:To determine the influence of antioxidation on plasma vitamin A,E,C following intraabdominal sepsis in rats. Methods:The model of cecal ligation and puncture(CLP) was used. Plasma vitamin A,E,C,malondialdehyde(MDA) and glutathione(GSH) were measured at 0,1,3,5 day after CLP,and the relation of their linear regression were analysed. Results:Plasma vitamin A,E,C and GSH were decreased and MDA was increased significantly after CLP.Plasma vitamin A was correlated with GSH and vitamin C,E were correlated with MDA significantly. Conclusions:The decreased antioxidation may be the main reason of vitamin A,E,C deficiency after sepsis. |
| |
| Keywords: | Vitamins Sepsis Antioxidation |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
