| 碳酸氢钠注射液进行细菌内毒素检查的研究 |
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| 引用本文： | 徐富培 李万玉. 碳酸氢钠注射液进行细菌内毒素检查的研究[J]. 中国药房, 2000, 11(2): 65-66 |
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| 作者姓名： | 徐富培 李万玉 |
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| 作者单位： | 重庆医科大学临床学院药剂科!重庆市400016 |
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| 摘 要： | 目的 :研究5 %碳酸氢钠注射液进行细菌内毒素检查的可行性。方法 :通过加浓盐酸中和样品溶液、沸水浴和冰浴后 ,再考察中和液对鲎试验的干扰性。结果 :中和液按1∶4稀释后 ,用灵敏度为0 125EU/ml的鲎试剂进行细菌内毒素检查无干扰。结论 :细菌内毒素检查法似可代替兔法热原检查。
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| 关 键 词： | 碳酸氢钠注射液 干扰试验 细菌内毒素检查法 热原 |
Detection of Bacterial Endotoxin in Sodium Bicarbonate Injection |
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| XU Fupei,LI Wanyu,ZHAO Yu. Detection of Bacterial Endotoxin in Sodium Bicarbonate Injection[J]. China Pharmacy, 2000, 11(2): 65-66 |
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| Authors: | XU Fupei LI Wanyu ZHAO Yu |
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| Abstract: | ATM:To study the feasibility of bacterial endotoxins test(BET)for 5% sodium bicarbonate injection.METHOD_S:After neutralized with concentrated hydrochloric acid,the sodium bicarbonate injection was bathed with the boiling water and the ice.The interference of the neutralization solution for BET was investigated.RESULTS:When the neutralization solution was diluted to four times,endotoxin could be assayed by TAL with the sensitivity of 0 125EU/ml.CONCLUSTON:The bacterial endotoxins test can replace the pyrogen test for the sodium bicarbonate injection. |
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| Keywords: | sodium bicarbonate injection interfering test bacterial endotoxin test pyrogen test |
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