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盐酸氯丙嗪注射液的HPLC测定
引用本文:陈镇生,韩加怡.盐酸氯丙嗪注射液的HPLC测定[J].中国医药工业杂志,1996,27(7):315-317.
作者姓名:陈镇生  韩加怡
作者单位:浙江省药品检验所
摘    要:采用苯基键合硅胶柱经HPLC测定盐酸氯丙嗪注射液的含量,平均回收率100.13%,RSD为0.85%。

关 键 词:盐酸氯丙嗪注射液,高效液相色谱法,测定

HPLC DETERMINATION OF CHLORPROMAZINE HYDROCHLORIDE INJECTION
Authors:CHEN Zhen-Sheng  HAN Jia-Yi
Abstract:An improved HPLC method is described for the quantitative determination of chlorpromazine hydrochloride injection. Using phenyl silica column and UV detector, with methanol-acetonitrile-0.02 mol/L potassium dihydrogen phosphate solution(100:150:350) as the mobile phase, an almost linear calibration curve was obtained(r=0.9999). The average recovery and RSD were 100. 13%, and 0.85%, respectively.
Keywords:chlorpromazine hydrochloride injection  HPLC  determination  
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