学龄期恶性肿瘤患儿生存质量及影响因素调查研究

目的 探讨学龄期恶性肿瘤患儿的生存质量及影响因素, 为提高其生存质量提供依据。方法 采取整群随机抽样方法, 抽取2011-2012年在北京市、唐山市8家三级甲等医院内就诊的白血病等恶性肿瘤患儿240名为研究对象, 应用PedsQL^TM4.0儿童生存质量普适性核心量表和PedsQL^TM3.0儿童癌症模块生存质量量表中文版进行调查。结果 6～8岁患儿的生理功能(37.28±11.67)、角色功能(51.72±11.43)、操作焦虑(40.24±11.51)和交流(42.32±10.57)低于9～11岁患儿(P<0.05);情感功能(59.43±14.53)、社会功能(54.69±12.61)、治疗焦虑(51.11±11.41)、担忧(64.19±12.49)和对外貌评价(70.14±11.67)高于9～11岁患儿(P<0.05)。影响恶性肿瘤患儿生存质量的多元逐步回归分析显示, 患儿年龄, 患病时间>2年, 住院次数≥3次进入回归方程(P<0.05)。结论 6～8岁恶性肿瘤患儿比9～11岁患儿需要更多的生理功能方面的照护, 而9～11岁患儿需要更多的情感支持, 住院次数的增加使学龄期恶性肿瘤患儿的生存质量下降。

Study on the quality of life of school-age children with malignant tumors and the influential factors.

Objective To investigate the quality of life of school-age children with malignant tumors and the influential factors analysis. Method A cluster random sampling method was conducted to recruit 240 children with leukemia and other malignancies in 8 first-class hospitals in Beijing and Tangshan from 2011 to 2012, and they were investigated by PedsQL^TM4.0 and PedsQL^TM3.0. Results 6~8 year-old children 's scores of physiological function (37.28±11.67), role function (51.72±11.43), operational anxiety (40.24±11.51), Communication (42.32±10.57) were below 9~11 year-old children (P all <0.05);while emotional function (59.43±14.53), social function (54.69±12.61), the anxiety of treatment (51.11±11.41), fear (64.19±12.49) and evaluation of appearance (70.14±11.67) were higher than 9~11 year-old children(P all<0.05).Multivariate stepwise regression analysis showed that child's age, disease duration>2 years, hospitalizations ≥ 3 times were into the regression equation (P<0.05). Conclusions 6~8 year-old children need more care in physiological function than 9~11 year-old children, while the 9~11 year-old children need more emotional support.The increasing times of hospitalizations of children with malignant tumor reduced children's quality of life.