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目的了解慢性胃炎患儿胃固体排空功能。方法对2008年1月至2012年1月首都儿科研究所附属儿童医院6～17岁因反复上腹部(或脐周)疼痛、上腹部不适伴有腹胀、嗳气、恶心、呕吐、早饱等消化道症状持续2个月以上,并且每周至少发作1次的儿童需要做胃镜检查者,进行电子胃镜常规检查,同时取病理活检并进行幽门螺杆菌(HP)检测。对确诊慢性胃炎的65例患儿行钡条胃固体排空试验,计算5h胃排空情况,收集服用钡条后24h的临床症状和体征。结果 HP感染总阳性率为27.7%,5h胃排空异常率HP阳性者占11.1%,HP阴性者占21.3%,两者差异无统计学意义(P>0.05)。HP阳性者无论是否有胃排空异常,其胃黏膜病理中-重度炎症者占66.7%。慢性胃炎患儿5h胃排空率<50%者占18.5%,胃排空率<75%者占23.1%。慢性胃炎患儿服用钡条后24h内均无任何异常症状和体征。结论部分慢性胃炎患儿存在胃动力障碍,临床症状不能完全反映胃固体排空情况。对于6～17岁儿童服用钡条行胃固体排空功能检查安全并符合自然生理状态。HP阳性者中-重度慢性胃炎发生率高。

Gastric emptying of solids in children with chronic gastritis.

??Objective To study the gastric emptying of solids in children with chronic gastritis. Methods From Jan.2008 to Jan.2012 in Capital Institute of Pediatrics??the children aged 6 to 17 years with recurrent upper abdominal??or cullen??pain??upper abdominal discomfort associated with bloating??belching??nausea??vomiting??early satiety lasting for 2 months or more??and the onset more than once per week were asked to undergo electric endoscopy??65 chronic gastritis patients were enrolled. The gastric emptying was measured by a radioscopic technique 5 h after a solid meal with radiopaque markers. Results HP positive patients accounted for 27.7%. There were no significant differences between HP positive patients and HP negative patients??11.1% and 21.3%?? respectively??P > 0.05??. Moderate and severe gastritis patients accounted for 66.7% in HP positive patients. For the postprandial 5 h emptying??18.5% children with chronic gastritis had less than 50% gastric emptying of solids??and 23.1% of them had less than 75% gastric emptying of solids. There were not any side effects of radiopaque markers in 24h in children with chronic gastritis. Conclusion Some of the children with chronic gastritis have gastro-obstraction??the clinical symptom hardly reflects the gastric emptying of solids. Radiopaque markers are safe and comply with its natural physiological state for children aged from 6 to 17. The incidence of moderate and severe gastritis is higher in HP positive patients than in mild gastritis.