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Ginsenoside Rs3, a genuine dammarane-glycoside from Korean red ginseng
Authors:Nam-In Baek  Jong Moon Kim  Jeong Hill Park  Jae Ha Ryu  Dong Seon Kim  You Hui Lee  Jong Dae Park  Shin Il Kim
Affiliation:(1) College of Industry, Kyung Hee University, Seochun-Ri 1, Kiheung-Eup, Yongin-Si, 449-701 Suwon, Kyunggi-Do, Korea;(2) College of Pharmacy, Seoul National University, 151-742 Seoul, Korea;(3) Department of Pharmacy, Sookmyung Women's University, 140-742 Seoul, Korea;(4) Korea Ginseng & Tobacco Research Institute, 305-345 Taejeon, Korea
Abstract:A genuine dammarane-glycoside, named as ginsenoside Rs3, was isolated from the MeOH extracts of Korean red ginseng (Panax ginseng C.A. Meyer) through repeated silica gel column chromatographies and its chemical structure was determined as (20S)-protopanaxadiol 3-O-6″-O-acetyl-β-D-glucopyranosyl (1→2)-β-D-glucopyranoside on the basis of several spectral and physical evidences including HMBC and FAB-MS.
Keywords:Panax ginseng            Genuine saponin  Red ginseng  Ginsenoside Rs3            HMBC
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