| 黄芪多糖和加味玉屏风汤对小鼠胸腺细胞凋亡抑制作用的比较 |
| |
| 引用本文： | 杨燕萍,胡冬根,陈新. 黄芪多糖和加味玉屏风汤对小鼠胸腺细胞凋亡抑制作用的比较[J]. 湖北中医药大学学报, 2001, 3(4): 34-35 |
| |
| 作者姓名： | 杨燕萍 胡冬根 陈新 |
| |
| 作者单位： | [1]湖北中医学院430061 [2]上海市安图医院 |
| |
| 基金项目： | 广东省中医药管理局资助项目 |
| |
| 摘 要： | 目的 研究黄芪多糖（APS）和加味玉屏风汤（MJSD）对小鼠胸腺细胞凋亡影响的效应差别。方法 采用荧光显微镜和流式细胞仪，分别检测相同浓度APS或MJSD共同培养前后胸腺细胞凋亡指数和细胞亚二倍体的变化，并进行横向比较。结果 发现MJSD和APS对胸腺细胞的自发凋亡及由地塞米松磷酸钠（Dex-p 10^-7M)诱导的胸腺细胞凋亡均有明显的抑制作用，且MJSD的作用优于APS。结论 MJSD的免疫调节作用优于APS。
|
| 关 键 词： | 黄芪多糖 加味玉屏风汤 胸腺细胞 细胞凋亡 抑制作用 |
| 文章编号： | 1008-987(2001)04-0034-02 |
| 修稿时间： | 2001-05-23 |
The Comparison of Inhibition by Astragalus Ploysaccharide and Modified Jade Screen Decoction on Murine Thymocyte Apoptosis |
| |
| Yang Yanping ,Hu Donggen ,Chen Xin .Hubei College of TCM.Wuhan. The Comparison of Inhibition by Astragalus Ploysaccharide and Modified Jade Screen Decoction on Murine Thymocyte Apoptosis[J]. Journal of Hubei University of Chinese Medicine, 2001, 3(4): 34-35 |
| |
| Authors: | Yang Yanping Hu Donggen Chen Xin .Hubei College of TCM.Wuhan |
| |
| Affiliation: | Yang Yanping 1,Hu Donggen 2,Chen Xin 3 1.Hubei College of TCM.Wuhan 430061 2.Antu Hospital Shanghai City.Shanghai 200093 3.American National Health Institute.MD21702 USA |
| |
| Abstract: | To investigate the comparison of inhibition by Astragalus ploysaccharide and modified jade screen decoction on murine thymocyte apoptosis.The changes of thymocyte apoptosis index and cell hypodiploid ratio were detected by fluorescence microscopy and flow cytometric analysis before and after the thymocytes were coincubated with MJSD or APS.Results came from the same concentration of MJSD and APS were compared.The results shew that MJSD and APS both had significant inhibition effect on thymocyte apoptosis happened spontaneously and induced by Dex p,and the effect of MJSD was better than that of APS.It demonstrated that the immunoregulation effect of MJSD is better than that of APS,APS and other component in MJSD cooperate in the effect. |
| |
| Keywords: | Astragalus ploysaccharide Modified jade screen decoction Thymocyto Cell death Inhibition |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
