重复经颅磁刺激治疗脑卒中后单侧空间忽略的研究进展

单侧空间忽略(USN)是脑卒中后最常见的行为认知障碍之一,以右侧大脑半球病变常见,预示着功能恢复的不良结果,对患者的生活质量有很大的负面影响。目前尚未有标准化治疗USN的方法,临床常采用营养支持、药物治疗(如多巴胺、去甲肾上腺素能激动剂)、康复训练、棱镜适应、虚拟现实等进行治疗。随着重复经颅磁刺激(rTMS)的发展,其作为一种无创、无痛、不良反应少、操作简单的非侵入性脑刺激技术,越来越多地应用于USN的治疗中。本文对国内外有关rTMS治疗USN的研究做一综述,以期为临床治疗USN提供依据。

Research progress of repetitive transcranial magnetic stimulation in the treatment of unilateral spatial neglect after stroke

Unilateral spatial neglect(USN)is one of the most common behavioral cognitive impairment after stroke,especially in the right hemisphere,which indicates the adverse outcome of functional recovery and has a great negative impact on the quality of life of patients.At present,there are no standardized methods for USN treatment.Nutrition support,drug therapy(such as dopamine,noradrenaline agonist),rehabilitation training,prism adaptation,virtual reality and other treatment are often used in clinical practice for treatment.With the development of repetitive transcranial magnetic stimulation(rTMS),as a noninvasive,painless,less adverse reactions and simple operation of noninvasive brain stimulation technology,it is more and more used in treatment of USN.This paper reviews the domestic and foreign study about rTMS in treatment of USN,in order to provide the basis for clinical treatment of USN.