左氧氟沙星联合奈替米星治疗呼吸道感染的临床效果

目的 分析左氧氟沙星联合奈替米星治疗呼吸道感染的临床效果.方法 选取2019年1月至2020年6月社旗县人民医院感染性疾病科收治的84例呼吸道感染患者,按奇偶数分组法将其分为对照组和观察组,各42例.对照组采用左氧氟沙星治疗,观察组采用左氧氟沙星联合奈替米星治疗.比较两组的治疗效果.结果 观察组的治疗总有效率为97.6...

Clinical effect of levofloxacin combined with netilmicin in the treatment of respiratory tract infection

Objective To analyze the clinical effect of levofloxacin combined with netilmicin in the treatment of respiratory tract infection.Methods A total of 84 patients with respiratory tract infection admitted in infectious diseases department of Sheqi people's hospital from January 2019 to June 2020 were selected and divided into control group and observation group according to odd even number grouping method,with 42 cases in each group.The control group was treated with levofloxacin,and the observation group was treated with levofloxacin combined with netilmicin.The therapeutic effects of the two groups were compared.Results The total effective rate of treatment in the observation group was 97.62%,which was higher than 78.57% of the control group,and the difference was statistically significant(P<0.05).The cough improvement time,wheezing improvement time,temperature review time and hospitalization time in the observation group were shorter than those in the control group,and the differences were statistically significant(P<0.05).After treatment,the levels of IL-4,IL-6 and TNF-α in the two groups were lower than those before treatment,and those in the observation group were lower than the control group,and the differences were statistically significant(P<0.05).There was no significant difference in the total incidence of adverse reactions between the two groups(P>0.05).The pathogen clearance rate in the observation group was 90.48%,which was higher than 71.43% in the control group,and the difference was statistically significant(P<0.05).Conclusion Levofloxacin combined with netilmicin in the treatment of respiratory tract infection has ideal effect,which can effectively improve the clinical symptoms and signs of patients,reduce the level of inflammatory factors,and less adverse reactions.