碳酸锂合用抗精神病药治疗精神分裂症患者攻击行为研究

目的 评价碳酸锂合用抗精神病药对精神分裂症患攻击行为的治疗作用。方法 对17例有攻击行为的长期住院精神分裂症患在原有抗精神病药的基础上加用碳酸锂进行为期6w的治疗，在开始治疗前及治疗第6w末用BPRS、MOAS进行评定。结果 (1)治疗前后BPRS各因子分比较，无显差异。(2)治疗后MOAS评分降低，治疗前后评分比较有显差异(P＜0．01)。结论 碳酸锂治疗精神分裂症的攻击行为安全有效。

Lithium carbonate combined with anti - psychotics in aggressive behaviors of schizophrenics

Objective To evaluate the efficacy of lithium carbonate combined with antipsychotics in the treatment of aggressive behaviors of schizophrenics. Method Seventeen inpatient schizophrenics with aggressive behaviors were treated with combination of lithium and antipsychotics for six weeks. Before treatment and in the 6th week of treatment, the patients were assessed with the BPRS and MOAS. Results (1). No significant difference were found among factor's scores of BPRS before and after treatment. (2) . After treatment, the MOAS score reduced , and the score comparison between pre - and post - treatment showed significant difference( P <0.01) . Conclusion Lithium carbonate is an effective and safe drug in the treatment of aggressive behaviors of schizophrenics.