Further Chromone Alkaloids from Schumanniophyton magnificum

Six further alkaloids have been isolated from the water-soluble fraction of the ethanolic extract of SCHUMANNIOPHYTON MAGNIFICUM Harms. Two of these are the known compounds trigonelline and rohitukine but the other four compounds are novel. Two of these, named schumagnine and N-methylschumagnine, consist of the chromone noreugenin linked to piperidine-related moieties whilst the other two are quaternary amines, the N-methyl analogues of schumanniophytine and isoschumanniophytine. The structures of these compounds have been deduced from their spectral characteristics and by chemical interconversions.