Malignant fibrous histiocytoma of the esophagus |
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| Authors: | Hiroshl Naganuma Haruo Ohtani Junzo Sayama Nobumitu Sakai Yukio Taira Daisuke Shibuya Atushi Miyazaki Hiroyuki Sakurada |
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| Institution: | Department of Pathology, Sendai City Hospital, Sendai, Japan;Department of Pathology, Tohoku University, School of Medicine, Sendai, Japan;Department of Surgery, Sendai City Hospital, Sendai, Japan;Department of Gastroenterology, Sendai City Hospital, Sendai, Japan |
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| Abstract: | A 78-year-old man presented with an esophageal polyp that was confirmed by Immunohistochemistry and electron microscopy to be malignant fibrous histiocytoma. The tumor was comprised of a proliferation of spindle-shaped cells admixed with bizarre giant cells. These tumor cells were immunoreactive for smooth muscle actin, vimentin, α-1-arrti-chymotrypsin and CD68. Electron microscopic examination revealed the myoflbroblastic and histtocytic features of the tumor cells. No elements of epithelial or myogenic differentiation were found in the tumor. Malignant fibrous histiocytoma of the esophagus is extremely rare, with 10 cases being documented so far in the literature. The differential diagnosis of pteomorphic tumors of the esophagus is discussed. |
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| Keywords: | esophagus electron microscopy immunohisto-chemistry malignant fibrous histiocytoma |
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