帕金森病患者实验记忆和日常生活记忆研究

Parkinson'sdisease(PD)isafamiliarage-relatedneurodegen-erativediseaseinolder,whichischaracterizedbyrestingtremor,cogwheelrigidity,bradykinesia,andposturalrefleximpairment.ResearchesrecentlyhaveshownclearevidencethatPDpatientshavememorydeficits犤1犦,andmemorydeficitisasensitiveindextotheinjuryordysfunctionofbrain.Nowstudyofmemorysuggeststhattherearemulti-memorysystemsinhumanbrain,andacuteorde-generativeinjuriesofparticularsystemsresultinparticularmemorydisabilities犤2犦.Thestudyofmnemonicchar…

Laboratory memory and everyday memory in patients with Parkinson's disease

Objective To study the recognition,recall and everyday memory in patients with Parkinson's disease.Methods 16 patients with idiopathic PD and 16 matched healthy control were examined using eight subtests of Multiple Memory Assessment Scale (MMAS) word recall, picture recall,picture reproduction,picture recognition,word recognition and everyday memory.Results Except for word recognition(P >0.05),the performances of patients were significantly worse in picture recall(P< 0.05),word recall (P< 0.01),picture reproduction(P< 0.01),picture recognition(P< 0.01),and everyday memory(P< 0.01) than those of normal control.The most memory performances of patients with Parkinson's disease were significantly negatively correlated with the score of Yale Extrapyramidal Symptom Scale(YESS).Conclusion The picture recognition,recall,and everyday memory of PD patients were impaired, and the impairment was related to the deficient function of the striatofrontal circuit.