74例低钾性周期性麻痹的病因、发病机制及临床分析

目的：探讨低钾性麻痹的病因、发病机制与临床特点。方法：通过临床资料、电生理和实验室检查，对74例低钾性麻痹病人进行系统分析。结果：低钾性麻痹多见于男性青壮年，与遗传因素有关；多为感染(38例，51．35％)、激烈活动(14例，18．92％)和饱餐(8例，10．81％)后休息中发作：典型症状为四肢对称性弛缓性瘫痪，患肌张力低．腱反射减弱或消失，发作时常有血钾及心电图改变，少数患可伴有呼吸肌麻痹、心悸等临床特点。结论：感染为该病的主要诱因，本病发病率低，但不能早期诊断和恰当治疗。有可能导致呼吸肌麻痹而死亡。

The observation on the causes,pathogenic mechanisms and characteristics for hypokalemic paralysis

Objective:To investigate the causes,pathogenesis and clinical characteristics of hypokalemic paralysis.Methods:After clinical data,electroneurophysiology and examination lab.37 patients with hypokalemic paralysis were observed and analysed.Results:The patients with hypokalemic paralysis was mostly mid-young people,and it was related to heredity;the hypokalemic paralysis attack showed most factor of infection(38case,51.35%),after eating too much(14case,18.92%),and acuity action(8case,10.81%)on sleeping;The clinical exponent symptoms showed extremity flaccid paralysis,hypotonia,tendon hyporeflexia or areflexia,accompanied with hypokalemic and changes of electrocardiogram(ECG).A few of attend breathe with difficulty and pant in patients with hypokalemic paralysis.Conclusion:A relationship was noted between the infection and hypokalemic paralysis,although the mortality rate was lower,yet it was unable to be early diagnosel and fitfully treated,it might be dead by breath muscle paralysis.