Studies on Ectopic ACTH-Producing Tumors: III. An Ectopic Melanocyte-Stimulating Hormone: Gel Chromatographic Finding and Time-Lapse Color Change of Frog Skin |
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| Authors: | NAKAMURA MASUHISA; TANAKA AKIRA; KAWABATA TOMOJI; YAMAMOTO HIRONOSUKE; IMURA HIROO |
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| Institution: | Shionogi Research Laboratory, Shionogi & Co., Ltd. Osaka, Japan
* The Third Division, Department of Medicine, Kobe University School of Medicine Kobe, Japan |
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| Abstract: | On isolation of the main melanocyte-stimulating factor fromthe metastatic liver tumor of islet cell carcinoma of the pancreas,it was found to be a peptide resembling human ß-MSHin the time-lapse skin darkening response of Xenopus frogs,but different in the volume of elution on Sephadex gel chromatography. |
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