| 养血清脑颗粒治疗蛛网膜下腔出血后脑供血不足的实验室研究 |
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| 引用本文： | 马琳,王国开. 养血清脑颗粒治疗蛛网膜下腔出血后脑供血不足的实验室研究[J]. 中国医院用药评价与分析, 2007, 7(4): 308-309 |
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| 作者姓名： | 马琳 王国开 |
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| 作者单位： | 天津医科大学第二医院神经外科,天津市,300211 |
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| 摘 要： | 目的:研究养血清脑颗粒对血管痉挛期的蛛网膜下腔出血(SAH)动物模型脑血流的影响。方法:枕大池注射尾动脉血建立大鼠SAH血管痉挛期模型,灌胃喂食不同剂量养血清脑颗粒,并采用激光多普勒仪测定其对鼠脑脑血流的影响。结果:不同剂量组给药后脑血流改变率差异有显著性,具有统计学意义。结论:养血清脑颗粒可以在血管痉挛期改善SAH鼠脑的脑血流供应,并存在一定的剂量相关性。
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| 关 键 词： | 养血清脑颗粒 蛛网膜下腔出血 脑血流 |
| 文章编号： | 1672-2124(2007)04-0308-02 |
| 修稿时间： | 2007-03-29 |
Yangxue Qingnao Granula for Insufficient Cerebral Blood-Supply after Subarachnoid Hemorrhage: An Empirical Study |
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| MA Lin,WANG Guokai. Yangxue Qingnao Granula for Insufficient Cerebral Blood-Supply after Subarachnoid Hemorrhage: An Empirical Study[J]. Evaluation and Analysis of Drug-Use in Hospital of China, 2007, 7(4): 308-309 |
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| Authors: | MA Lin WANG Guokai |
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| Abstract: | OBJECTIVE: To study the effects of Yangxue Qingnao Granula on cerebral blood flow in subarachnoid hemorrhage(SAH) model rats during angiospasm.METHODS: The cisterna magna of rats were injected with arteria caudilis blood to establish SAH model(during angiospasm);then the rats were administered intragastrically with different dosage of Yangxue Qingnao Granula,and the effects of which on cerebral blood flow in rats were detected by laser-Doppler.RESULTS: There were significant differences in cerebral blood flow improvement rate among different dosage groups.CONCLUSION: Yangxue Qingnao Granula can dose-dependently improve the cerebral blood flow in SAH model rats during angiospasm. |
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| Keywords: | Yangxue Qingnao Granula Subarachnoid hemorrhage Cerebral blood flow |
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