胰腺神经内分泌肿瘤的CT表现及良恶性的鉴别诊断

目的总结胰腺神经内分泌肿瘤CT表现的特点及良恶性鉴别诊断方法。方法选择我院2010年1月-2015年10月期间收治36例经手术病理证实的胰腺神经内分泌肿瘤患者作为研究对象,均行螺旋CT三期扫描,总结胰腺神经内分泌肿瘤的CT表现及良恶性肿瘤鉴别方法。结果功能性胰腺神经内分泌肿瘤的CT平扫以等密度结节为主,增强扫描强化明显,无功能胰腺神经内分泌肿瘤多体积大,多见完整包膜结构,动脉期以不均匀或环形增强为主。实性患者动脉期强化形式均为中度或明显强化,囊性/囊实性患者则以轻度强化为主54.6%(6/11),差异有统计学意义(P0.05)。结论功能性与无功能胰腺神经内分泌肿瘤的CT表现均存在一定特征,可帮助临床诊断提供有用信息,且良恶性的鉴别诊断也有一定规律可循,利于提高诊断准确性,实现早期确诊。

CT Findings of Pancreatic Neuroendocrine Tumors and Differential Diagnosis of Benign and Malignant Tumors

Objective To summarize the characteristics of CT findings of pancreatic neuroendocrine tumors and differential diagnosis of benign and malignant tumors. Methods 36 patients with pancreatic neuroendocrine tumors confirmed by operation and pathology in our hospital from January 2010 to October 2015 were selected as the study object and all underwent spiral CT three phase scan. The CT findings of pancreatic neuroendocrine tumors and differential methods of benign and malignant tumors were summarized.Results The CT findings of functional pancreatic neuroendocrine tumors mainly were equal-density nodules and after enhanced scan, the enhancement was significant while those of non-functional pancreatic neuroendocrine tumors were large volume, visible complete envelope structures and in arterial phase, mainly was inhomogeneous or annular enhancement. The enhancement forms in arterial phase of patients with solid tumors were moderate or significant while of patients with cystic / cystic solid mainly were mild 54.6% (6/11)] (P<0.05).Conclusion The CT findings of functional and non-functional pancreatic neuroendocrine tumors have certain characteristics which can provide useful information for clinical diagnosis. Besides, the differential diagnosis of benign and malignant tumors also has certain rules to follow, which is beneficial to improve diagnostic accuracy and realize early diagnosis.