| 氟烷,甲氧氟烷,氨氟醚和异氟醚麻醉在边缘系统的定位 |
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| 引用本文： | 徐礼鲜 李军. 氟烷,甲氧氟烷,氨氟醚和异氟醚麻醉在边缘系统的定位[J]. 医学争鸣, 1997, 18(6): 539-542 |
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| 作者姓名： | 徐礼鲜 李军 |
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| 作者单位： | 第四军医大学口腔医学院麻醉科!西安，710033，第四军医大学口腔医学院麻醉科!西安，710033，第四军医大学口腔医学院麻醉科!西安，710033，第四军医大学口腔医学院麻醉科!西安，710033，第四军医大学口腔医学院麻醉科!西安，710033，第四军医大学口腔医学院麻醉科!西安，710033，第四军医 |
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| 基金项目： | 国家自然科学基金!39470674 |
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| 摘 要： | 目的：了解吸入麻醉在边缘系统的作用部位，为进一步探讨吸入麻醉作用机理打基础。
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| 关 键 词： | 吸入麻醉剂 边缘系统 免疫组织化学 氟烷 |
The Position of methaxyflurane, halothane, enflurane and isoflurane anesthesia within limbic system of the rat |
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| Xu Lixian, Li Jun, Zhang Xiao feng, Zhang hui, Lu Lingling, Zhang Guoliang, Sun Hui,Zhang hongkai. The Position of methaxyflurane, halothane, enflurane and isoflurane anesthesia within limbic system of the rat[J]. Negative, 1997, 18(6): 539-542 |
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| Authors: | Xu Lixian Li Jun Zhang Xiao feng Zhang hui Lu Lingling Zhang Guoliang Sun Hui Zhang hongkai |
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| Abstract: | To study the distribution of c-fos oncogene expression within limbic system during methaxyflurane, halothane,enflurane and isoflurane anesthesia. Methods: C-fos oncogene immunohistochemical technique (ABC method) was employed. Results: When the fourth inhalating anesthetic's concentration was 2%, most of the Fos like immunoreactive neurons(FLN), appeared in bed nucleus of the striaterminalis, field CA1 of Ammon's horn, field CA2 of Ammons horn, basolateral amygdaloid nucleus, basomedial amygdaloid nucleus, central amygdaloid nucleus, islands of Calleja, lateral habenular nucleus, medial habenular and lateral septal nucleus. Conclusion: The results indicate that FLNs participate in the process of inhalation anesthesia,which necessitates and paves the way for further study of the patterns of linkage and the mechanism of interaction between functional nuclei. |
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| Keywords: | inhalation anesthetic limbic system c-fos oncongne immunohistochemistry |
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