宫颈癌患者放化疗期间睡眠障碍发生情况及影响因素分析

目的:分析宫颈癌患者放化疗期间睡眠障碍发生情况及影响因素。方法:选取2016年5月至2019年5月滨州医学院、山东省第二人民医院接收诊治的宫颈癌患者62例作为研究对象,所有患者均接受放疗与化疗治疗,治疗期间,采用匹兹堡睡眠质量指数量表(PSQI)观察宫颈癌患者睡眠障碍发生情况。结果:宫颈癌患者放化疗期间发生睡眠障碍32例,发生率51. 61%。Logistic多因素回归分析显示,治疗环境噪音超标、重度疼痛、肿瘤分期(Ⅳ期)是宫颈癌患者放化疗期间发生睡眠障碍的独立危险因素(P <0. 05)。结论:宫颈癌患者放化疗期间睡眠障碍发生率较高,噪音环境、疼痛严重程度、病情恶化程度等是其睡眠障碍的主要影响因素。

Occurrence and Influencing Factors of Sleep Disorders in Patients Undergoing Radiotherapy and Chemotherapy for Cervical Cancer

Objective:To analyze the occurrence and influencing factors of sleep disorders in patients treated with radiotherapy and chemotherapy for cervical cancer.Methods:From May 2016 to May 2019,a total of 62 cervical cancer patients treated with radiotherapy and chemotherapy in the 2nd People′s Hospital of Shandong Province were enrolled.During treatment,the Pittsburgh Sleep Quality Index(PSQI)was used to analyze the incidence of sleep disorders.Results:Thirty-two cases developed sleep disorders during radiotherapy and chemotherapy,with an incidence of 51.61%.Multivariate logistic regression analysis showed that excessive noise from treatment environment,severe pain,and tumor stage(stageⅣ)were independent risk factors for sleep disorders(P<0.05).Conclusion:Noise,severe pain and disease deterioration are main factors of high sleep disorder incidence in cervical cancer patients undergoing radiotherapy and chemotherapy.