冠心病患者血尿酸检测的临床意义

目的：探讨冠心病患者血尿酸检测的临床意义。方法：对我院2007～2009年收治的100例冠心病患者（冠心病组）和55例健康体验者（对照组）采用自动生化分析仪检测冠心病患者及非冠心病患者体内血尿酸（UA）的变化。用氧化酶法测定总胆固醇（TC）和三酰甘油（TG）、高密度脂蛋白-胆固醇（HDL—C）、低密度脂蛋白-胆固醇（LDL—C），并对各项参数进行统计分析。结果：冠心病组UA浓度（455．24μmol，L）与对照组（341．29μmol／L）比较，有极显著性差异（P〈0．01）。结论：UA与心血管事件的发生密切相关。UA浓度的增高可作为冠心病发病的一个独立高危因素，是冠心病患者病情严重程度的一个重要指标，对其进行早期干预，有可能预防心血管事件的发生。

Clinical significance of serum uric acid in the patients with coronary heart disease

Objective： To investigate the clinical significance of serum uric acid in the patients with coronary heart disease. Methods： 100 cases of patients with coronary heart disease and 55 healthy experience from year 2007 to year 2009 in our hospital were detected the changes of serum uric acid （UA） with automatic biochemical analyzer. Total cholesterol by oxidation （TC）, triglyceride （TG）, high-density lipoprotein-cholesterol （HDL-C）, low-density lipoprotein cholesterol （LDL- C） were detected by enzymatic determination, and the statistical parameters were analyzed. Results： The UA concentrations in patients with coronary heart disease （455.24 μmol/L） was significantly higher than that of the control group （341.29 μmol/L） （P〈0.01）. Conclusion： The UA and cardiovascular events are closely linked. Serum UA concentration elevated can be used as an independent coronary heart disease risk factor. It is an important indicator for severity of coronary heart disease. For its early intervention, it is possible to prevent the occurrence of cardiovascular events.