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377例药品不良反应报告分析
引用本文:孙京峰,祝培友,王珂.377例药品不良反应报告分析[J].中国药物警戒,2006,3(4):213-214,217.
作者姓名:孙京峰  祝培友  王珂
作者单位:山东省淄博市第一医院,山东,淄博,255200
摘    要:目的 了解我院药品不良反应发生规律和特点,为临床提供药品安全性信息。方法 采用回顾性研究方法,对我院377例药品不良反应报告进行汇总分析。结果377例报告中,男女性别比例无明显差异,60岁以上患者的ADR发生率高于其他年龄段;发生不良反应的药品以抗微生物药最多见;累及系统-器官以皮肤及其附件的损害最多见,严重不良反应为过敏性休克。结论 加强药品不良反应监测,抗微生物药品是不良反应监测的重点,提高临床安全用药意识,确保患者用药安全。

关 键 词:药品不良反应  分析  抗微生物药  中药注射剂
文章编号:1672-8629(2006)04-0213-02
收稿时间:2006-02-23
修稿时间:2006-02-23

Analysis of 377 ADR reports
SUN Jing-feng,ZHU Pei-you,WANG Ke.Analysis of 377 ADR reports[J].Chinese JOurnal of Pharmacovigilance,2006,3(4):213-214,217.
Authors:SUN Jing-feng  ZHU Pei-you  WANG Ke
Institution:No. 1 hospital of Zibo Municipality Shandong Zibo 255200,China
Abstract:Objective To provide drug safety information for doctor's clinical practice, we need know orderliness and characteristics of occurrence of ADR in our hospital. Method We conducted a retrospective study to analyze 377 ADR reports in our hospital. Result There is no significant difference between male and famale, but the inci-dence rate of ADR in the age group above 60 is higher than other age groups. The majority of occurred ADR is related to antimicrobial drugs. Skin and its adjunct are likely to be the most affected organ. The most serious ADR is allergic shock. Conclusion In order to improve the awareness of clinical drug safety for doctors and ensure drug safe use of drugs in patients, ADR monitoring should be strengthened, especially ADR caused by antimicrobial drugs.
Keywords:Adverse Drug Reaction  reports  analysis
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