HIV Incidence in Young Girls in KwaZulu-Natal, South Africa-Public Health Imperative for Their Inclusion in HIV Biomedical Intervention Trials |
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| Authors: | Quarraisha Abdool Karim Ayesha B. M. Kharsany Janet A. Frohlich Lise Werner Mukelisiwe Mlotshwa Bernadette T. Madlala Salim S. Abdool Karim |
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| Affiliation: | Centre for the AIDS Programme of Research in South Africa (CAPRISA), Doris Duke Medical Research Institute, Nelson R Mandela School of Medicine, University of KwaZulu-Natal, 2nd Floor, Private Bag 7, Congella, Durban, 4013, South Africa. |
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| Abstract: | Young women are particularly vulnerable for acquiring HIV yet they are often excluded from clinical trials testing new biomedical intervention. We assessed the HIV incidence and feasibility of enrolling a cohort of young women for potential participation in future clinical trials. Between March 2004 and May 2007, 594 HIV uninfected 14-30?year old women were enrolled into a longitudinal HIV risk reduction study in KwaZulu-Natal, South Africa. The overall HIV prevalence at screening in young girls below the age of 18?years was 27.6?% compared to 52.0?% in the women above 18?years, p?
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