| 老年心衰患者血清sIL—2R及T细胞亚群的变化 |
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| 引用本文： | 刘志高 张中平. 老年心衰患者血清sIL—2R及T细胞亚群的变化[J]. 实用老年医学, 1998, 12(3): 112-113 |
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| 作者姓名： | 刘志高 张中平 |
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| 作者单位： | 同济医科大学附属梨园医院内科(刘志高)，武钢第一职工医院(张中平) |
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| 摘 要： | 目的研究老年心衰（ＨＦ）患者血清中可溶性白细胞介素－２受体（ｓＩＬ－２Ｒ）及Ｔ淋巴细胞亚群（Ｔ－ＬＳ）的变化及临床意义。方法血清ｓＩＬ－２Ｒ测定采用酶联免疫吸附双抗体夹心法，Ｔ－ＬＳ采用抗体致敏的红细胞花环法。检测４０例老年ＨＦ及３０例正常组血清ｓＩＬ－２Ｒ及Ｔ－ＬＳ的变化。结果老年ＨＦ患者血清ｓＩＬ－２Ｒ水平与正常组比较显著增高（Ｐ＜０．０５，Ｐ＜０．０１）；Ｔ－ＬＳ在老年ＨＦ与正常组比较显著下降（Ｐ＜０．０５，Ｐ＜０．０１）。结论血清ｓＩＬ－２Ｒ水平及细胞免疫低下可影响老年ＨＦ的发病及预后
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| 关 键 词： | 心衰 白细胞介素－2受体 T淋巴细胞亚群 |
The changes in serum sIL 2R and T lymphocyte subsets in elderly heart failure patients |
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| Liu Zhigao,Zhang Zhongpin. The changes in serum sIL 2R and T lymphocyte subsets in elderly heart failure patients[J]. Practical Geriatrics, 1998, 12(3): 112-113 |
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| Authors: | Liu Zhigao Zhang Zhongpin |
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| Affiliation: | Liu Zhigao,Zhang Zhongpin. Department of Internal Medicine,Liyuan Hospital,Tongji Medical University,Wuhan 430077 |
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| Abstract: | bjective To study the changes in and the clinical significance of serum soluble interleukin 2 receptor(sIL 2R) and T lymphocyte subsets (T LS) in elderly heart failure (HF) patients. Methods T LS in serum was measured by antibody sensitized red cell rosette test and serum sIL 2R,by double antibody enzyme linked immunosorbent assay. The difference in serum sIL 2R and T LS values between 40 elderly HF patients and 30 normal subjects (NC) were analysed. Results The serum sIL 2R value was significantly higher and T LS significantly lower in elderly HF patients than in NC( P <0 05, P <0 01,respectively). Conclusions The results demonstrated that a lower cell immunocompetence and a higher serum sIL 2R level might be involved in the pathogenesis and prognosis of elderly HF patients. |
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| Keywords: | Heart failure Interleukin 2 receptor T lymphocyte subsets |
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