Effects of ubiquinone-10 on energy metabolism and lipid peroxidation in rats with myocardial ischemia |
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| Authors: | V. N. Krylov L. D. Luk’yanova A. S. Koryagin E. V. Yastrebova |
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| Affiliation: | (1) Department of Human and Animal Physiology and Biochemistry, N. I. Lobachevskii Nizhny Novgorod State Medical University, Russia;(2) Laboratory of Bioenergetics, Institute of Pharmacology, Russian Academy of Medical Sciences, Russia |
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| Abstract: | Preventive and therapeutic intraventricular administration of ubiquinone-10 to male rats with epinephrine-induced myocarditis increased the rate of oxidative phosphorylation, elevated the content of ATP, and inhibited lipid peroxidation in ischemic myocardium. Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 130, No. 7, pp. 35–38, July, 2000 |
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| Keywords: | myocardial ischemia oxidative phosphorylation lipid peroxidation ubiquinone-10 |
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