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D-二聚体胶乳试验在血栓性疾病早期诊断中的应用
引用本文:安肇璋,杨绍敏,张曼华. D-二聚体胶乳试验在血栓性疾病早期诊断中的应用[J]. 上海医学检验杂志, 1996, 0(3)
作者姓名:安肇璋  杨绍敏  张曼华
作者单位:昆明市第一人民医院检验科
摘    要:
采用D-二聚体(D-D)胶乳试验,检测52例正常人,30例心血管疾病、28例肺心病、25例脑梗塞、20例DIC、41例脑外科手术和20例其它疾病的患者。结果表明D-D水平除肺心病缓解期和脑外科手术前与正常对照比较P>0.05外,其余均有显著性差异(P<0.005,P<0.05)。D-D胶乳法与传统的止凝血检验相比较,对血栓性疾病的早期诊断有较高的特异性(60.3%)和敏感性(90.6%),能提示继发性纤溶亢进,具有一定的临床意义和实用价值。

关 键 词:D-二聚体,血栓栓塞,纤维蛋白溶解

Application of D-dimer latex assay in the early diagnosis of thrombotic diseases
. An Zhaozhang, YangShaoming and Zhang Manhua.. Application of D-dimer latex assay in the early diagnosis of thrombotic diseases[J]. Shanghai Journal of Medical Laboratory Sciences, 1996, 0(3)
Authors:. An Zhaozhang   YangShaoming  Zhang Manhua.
Abstract:
Plasma D-dimer was determined by latex assay in patients with cardiovascular diseases (30), cor pulmonale(28), cerebral infarction (25), disseminated intravascular coagulation (20), surgical operation of brain (41) and other diseases (20), and normal adults (52). Results showed that in comparison to normal adults the D-dimer levels exhibited significant difference (P<0. 05, P<0.005) in all above diseases expect in alleviatory period of cor pulmonale and before surgical operation of brain (P>0. 05). D-dimer latex assay has higher specificity (60.3%) and sensitivity (90.6%) for the early diagnosis of thrombotic diseases than the traditional assays.
Keywords:D-dimer  Thrombosis  Fibrinolysis
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