老年与中青年突发性聋的疗效比较

目的 了解老年与中青年突发性聋患者的不同临床特征和疗效。方法 回顾分析123例（129耳）突发性聋资料，分成两组：老年组（60≥岁）72例（76耳），中青年组（＜60岁）51例（53耳）。所有患者行皮质类固醇激素、能量合剂等治疗，一部分患者加用高压氧和东菱克栓酶辅助治疗，5例上述治疗无效患者行甲强龙鼓室灌注治疗。结果分析用χ2检验和ｔ检验。结果 两组治疗后的总有效率（痊愈、显效、有效之和）分别为59.2％和69.8％，差异无统计学意义（χ2＝3.26，P＞0.05），总显效率（痊愈、显效之和）为34.2％和56.6％，差异有统计学意义（χ2＝6.37，P＜0.05）。患者发病至就诊时间差异有统计学意义（t=2.14，P＜0.05）。治疗前健患侧听力差分别为(28.5±13.9)dB和(42.1±28.2)dB ，差异有统计学意义（t=3.64，P＜0.01）。老年组患者合并糖尿病、高血脂症（25/76，48/76）的比例较中青年组（9/53，12/53）高。结论 老年突发性聋患者往往有基础的听力损失，发病呈渐进性和隐匿性,虽然总有效率与中青年患者相似，但显效率较低。类固醇激素鼓室灌注经圆窗渗透对一般治疗无效的部分患者仍有效。

Terapeutic effects of sudden sensorineural hearing loss in old and young

Objective To explore the clinical features of sudden sensorineural hearing loss(SSHL) between old and young wrinkly patients. Methods A retrospective review of 123 cases (129ears)of SSHL was carried out. All patients were classified into two groups: group A(76ears, over 60years old) and group B(53ears, younger than 60years old). All cases were treated with steroids and energy composition. Some were treated with a hyperbaric oxygen chamber and additional Batroxobin. 5 cases which failed these routine therapies were treated with intratympanic steroid therapies. A Partnership t test and Chi square test were used for analysis. Result The total effective rate of the two groups was 59.2% and 69.8% (P＞0.05). The total excellence rate of the elder was significant lower than that of the young(34.2% vs 56.6%) (P＜0.05). The mean duration before initiation of treatment was significantly different between the two groups(t=2.14，P＜0.05). The opposite ear′s hearing threshold level was significantly higher in the elder than in the young. Diabetes and Hyperlipemia was more frequently in the group of elder than in the group of young. Conclusions SSHL in the old gradually and hidingly unobserved initiates and often causes based hearing impairment in both affected and opposite ear.Though the total effective rate is not significantly different between two groups, the excellence rate is significantly lower in the older than in the younger. Intra-tympanic steroid therapy is useful in some patients who fail routine therapy.