不同喂养方式对早产小于胎龄儿骨密度的影响

目的 研究不同喂养方式对早产小于胎龄儿（ SGA）骨密度的影响。方法 将215例小于胎龄儿按照喂养方式分为5组：早产儿出院后配方奶喂养组、母乳喂养组、足月儿配方奶喂养组、母乳＋早产儿出院后配方奶喂养组、母乳＋足月儿配方奶喂养组，比较各组在生后第6月、12月骨密度值。结果 5组小于胎龄儿的骨密度数值从高到低依次为：母乳＋早产儿出院后配方奶喂养组、母乳喂养组、早产儿出院后配方奶喂养组、母乳＋足月儿配方奶组、足月儿配方奶喂养组，差异具有统计学意义（6月龄时：F男＝2．845，F女＝2．570；12月龄时：F男＝2．737，F女＝7．461，均P＜0．05）。结论 对早产小于胎龄儿童进行母乳喂养或强化母乳喂养能改善其骨密度情况，适用于早产儿。

Influence of different feeding patterns on bone mineral density of preterm small for gestational age infants

Objective To study the influence of different feeding patterns on bone mineral density of preterm small for gestational age （SGA） infants.Methods Totally 215 preterm SGA infants were divided into 5 groups：group A fed with formula for preterm infants after discharge, group B fed with breast milk , group C fed with formula for full-term infants, group D fed with breast milk and formula for preterm infants after discharge , and group E fed with breast milk formula for full-term infants.The bone mineral density of different groups was compared at 6 and 12 month of age .Results The bone mineral density of SGA infants was highest in group D , followed by group B , group A, group E and group C in order .The difference was significant （6 month of age：Fmale =2.845,Ffemale =2.570;12 month of age：Fmale =2.737, Ffemale =7.461, all P〈0.05）.Conclusion Breastfeeding or strengthened breastfeeding can improve the bone density of preterm SGA infants .This feeding pattern is more applicable for preterm SGA infants .