双侧卵巢巧克力囊肿剔除术对卵巢功能的影响

目的 探讨腹腔镜下双侧卵巢巧克力囊肿剔除术对卵巢储备功能的影响，并分析其敏感指标。方法 选择2010年1月至2012年1月期间来青岛市妇女儿童医院进行诊治的双侧卵巢巧克力囊肿且对生育有要求的患者94例为研究对象，所有患者均行腹腔镜下双侧卵巢巧克力囊肿剔除术。回顾性分析患者的临床资料，并根据其术后6个月的基础卵泡刺激素（ bFSH）水平分为卵巢储备功能下降组（bFSH≥10IU／L，18例）和卵巢储备功能正常组（bFSH＜10IU／L，76例）。术后分析敏感指标对各组卵巢储备功能的影响及妊娠结果。结果 卵巢储备功能下降组的年龄及囊肿分型构成与卵巢储备功能正常组相比差异均有统计学意义（t＝6．877，χ^2=7．243，均P＜0．05）；卵巢储备功能下降组的术前癌抗原125（CA125），术后CA125，术前用药，囊肿直径，合并深部浸润型子宫内膜异位症（ DIE）、腹膜型子宫内膜异位症（ PEM）、子宫腺肌症（ AM）情况及妊娠率与卵巢储备功能正常组相比差异均无统计学意义（均P＞0．05）。结论 腹腔镜下双侧卵巢巧克力囊肿剔除术对卵巢的储备功能有影响，年龄较大及多房囊肿患者术后卵巢储备功能下降的风险更高。

Influence of bilateral ovarian chocolate cystectomy on ovarian reserve function

Objective To investigate the influence of laparoscopic bilateral ovarian chocolate cystectomy on ovarian reserve function and the sensitive indicators .Methods From January 2010 to January 2012 94 patients diagnosed with bilateral ovarian chocolate cyst in Qingdao Women and Children Hospital and having requirement on birth were chosen , and they performed laparoscopic bilateral ovarian chocolate cystectomy.The clinical data of them were analyzed , and the patients were divided into decreased ovarian reserve function group （ bFSH≥10IU/L, 18 cases） and normal ovarian reserve function group （bFSH 〈10IU/L, 76 cases）.The influence of sensitive indicators on ovarian reserve function of both groups and the pregnancy outcomes were analyzed .Results The differences in cyst type and patients ’ age were significant between two groups （t=6.877, χ^2=7.243,P〈0.05）.There were no significant differences in CA125 before surgery, CA125 after surgery, premedication, cyst diameter, deeply infiltrating endometriosis （ DIE ）, peritoneal endometriosis （ PEM ）, adenomyosis （AM） and pregnancy rate between two groups （all P 〉0.05）.Conclusion Laparoscopic bilateral ovarian chocolate cystectomy will affect ovarian reserve function .Old patients with multi-room cyst have higher risks of ovarian reserve function decreased .