| 补肾益骨方辨证加减联合碳酸钙D3片对围绝经期骨质疏松症患者疗效及其对骨代谢指标的影响 |
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| 引用本文： | 战美玲,田永萍.补肾益骨方辨证加减联合碳酸钙D3片对围绝经期骨质疏松症患者疗效及其对骨代谢指标的影响[J].中国中医基础医学杂志,2019(8):1115-1118. |
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| 作者姓名： | 战美玲 田永萍 |
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| 作者单位： | 甘肃金昌市金川公司医院;甘肃中医药大学附属医院 |
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| 摘 要： | 目的:探讨补肾益骨方辨证加减联合碳酸钙D3片对围绝经期骨质疏松症患者的临床作用。方法:将120例围绝经期骨质疏松症患者按随机数字表法分为试验组与对照组各60例,对照组碳酸钙D3片治疗,试验组另加补肾益骨方辨证加减治疗,比较中医证候积分、临床疗效、骨密度(BMD)与血清抗酒石酸酸性磷酸酶5b(TRACP 5b)、骨特异性碱性磷酸酶(BAP)、Ⅰ型胶原C端肽(CTX-Ⅰ)、骨钙素(BGP)、促卵泡生成激素(FSH)、雌二醇(E2)水平和骨折发生情况。结果:试验组治疗后中医证候积分及血清TRACP 5b、CTX-Ⅰ、FSH水平均明显低于治疗前及对照组,试验组治疗后L1-L4腰椎、左侧股骨颈的BMD及血清BAP、BGP、E2水平均明显高于治疗前及对照组,试验组总有效率高于对照组,而治疗后1年内骨折发生率低于对照组差异显著。结论:补肾益骨方辨证加减联合碳酸钙D3片可明显改善围绝经期骨质疏松症患者临床症状、骨代谢及雌激素水平,提高骨密度疗效显著,并可预防骨折。
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| 关 键 词： | 补肾益骨方 碳酸钙D3片 围绝经期 骨质疏松症 骨代谢 雌激素 |
Effect and Influence on Bone Metabolism Indexes of Bushenyigu Recipe Syndrome Differentiation Addition and Subtraction Combined with Calcium Carbonate and Vitamin D3 Tablets on Patients with Perimenopausal Osteoporosis |
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| ZHAN Mei-ling,TIAN Yong-ping.Effect and Influence on Bone Metabolism Indexes of Bushenyigu Recipe Syndrome Differentiation Addition and Subtraction Combined with Calcium Carbonate and Vitamin D3 Tablets on Patients with Perimenopausal Osteoporosis[J].Chinese Journal of Basic Medicine In Traditional Chinese Medicine,2019(8):1115-1118. |
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| Authors: | ZHAN Mei-ling TIAN Yong-ping |
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| Institution: | (Jinchuan company hospital in jinchang, gansu province, Gansu jinchang 737100, China;Affiliated hospital of gansu university of Chinese medicine, Lanzhou 730000, China) |
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| Abstract: | ZHAN Mei-ling;TIAN Yong-ping(Jinchuan company hospital in jinchang, gansu province, Gansu jinchang 737100, China;Affiliated hospital of gansu university of Chinese medicine, Lanzhou 730000, China) |
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| Keywords: | Bushenyigu recipe Calcium Carbonate and Vitamin D3 Tablets Perimenopause Osteoporosis Bone metabolism Estrogen |
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