中西医结合治疗围绝经期功能失调性子宫出血

目的分析中西医结合治疗围绝经期功能失调性子宫出血的疗效及对子宫内膜厚度的影响。方法选取我院2016年3月-2017年3月收治的78例围绝经期功血患者,随机分为对照组和观察组,各39例。对照组给予刮宫术进行治疗,术后使用去氧孕烯炔雌醇片口服;观察组在对照组的基础上,联合使用补肾固冲汤进行治疗,2组均以12周为1个治疗疗程。比较2组治疗前后临床疗效结果,子宫内膜厚度变化情况和雌二醇、孕酮、黄体生成素、卵泡刺激素等水平变化情况。结果观察组治疗后总有效率为97.44%,显著高于对照组患者的84.62%(P<0.05)。治疗6周和治疗结束后,2组子宫内膜厚度均较本组治疗前显著降低(均P<0.05),且观察组子宫内膜厚度较同期对照组显著降低(均P<0.05)。2组治疗后各项性激素水平均显著低于本组治疗前(均P<0.05);且观察组各项性激素水平均显著低于对照组(均P<0.05)。结论中西医结合治疗围绝经期功血与单纯使用西药治疗比较,能够更加有效地改善患者雌激素分泌情况和出血症状,降低患者的子宫内膜厚度。

Treatment of Perimenopausal Dysfunctional Hemorrhage with Combination of Traditional Chinese and Western Medicine

Objective To analyze the effect of integrated traditional Chinese and western medicine on perimenopausal dysfunctional blood and its effect on endometrial thickness. Methods Select our hospital from March2016 to March 2016 at the records of 78 cases during the menopausal transition function in patients with blood,and according to random number table method to all of the patients were randomly divided into control group and observation group, each 39 cases. The control group patients were given curettage surgery treatment, postoperative use of desogestrel and oral ethinylestradiol piece. Patients in the observation group were treated on the basis of the treatment of the patients in the control group, and the patients were treated with a combination of Bushen Guchong decoction. Both groups were treated with a treatment course for 12 weeks. The results of clinical efficacy, endometrial thickness and estradiol, progesterone, luteinizing hormone and follicle stimulating hormone were compared before and after treatment. Results After treatment, the total effective rate was 97.44%, which was significantly higher than86.62% in the control group(P < 0.05). After 6 weeks and two groups after treatment in patients with endometrial thickness were significantly lower than group before treatment(all P < 0.05), the endometrial thickness of the patients in the experimental group was significantly lower than that in the control group(all P < 0.05). The two groups of patients after treatment of the sex hormone levels were significantly lower than before in our group(all P < 0.05), after treatment, all the sex hormone levels in the experimental group were significantly lower than those in the control group(all P < 0.05). Conclusion The combination of traditional Chinese and western medicine in the treatment of peri-menopausal dysfunctional patients is more effective in improving the estrogen secretion and bleeding symptoms than using western medicine alone, and significantly reducing the endometrial thickness of the patients.