小剂量氯胺酮在异位妊娠失血性休克病人麻醉诱导中的应用

目的：探讨小剂量氯胺酮用于异位妊娠破裂合并失血性休克病人全麻诱导时的循环情况。方法：异位妊娠破裂合并失血性休克女性患者60例,随机均分2组,Ⅰ组麻醉采用咪唑安定0.05 mg/kg,氯胺酮0.5 mg/kg,芬太尼0.005mg/kg,万可松0.1 mg/kg诱导插管;Ⅱ组麻醉采用咪唑安定0.05 mg/kg,芬太尼0.005 mg/kg,万可松0.1 mg/kg诱导插管。监测并记录麻醉诱导前、气管插管前的心率（HR）、收缩压（SBP）、舒张压（DBP）。结论：小剂量氯胺酮用于异位妊娠破裂合并失血性休克病人全麻诱导时,循环相对稳定,麻醉效果满意。

Application of minor dose Ketamine on hemorrhagic shock patients caused by ruptured ectopic pregnancy during the induction of anesthesia

Objective：To discuss clinical effect of minor dose Ketamine on hemorrhagic shock patients caused by ruptured ectopic pregnancy during the induction of general anesthesia. Methods ：A total of 60 patients were randomly divided into two groups： group 1, ketamine （0.5 mg/kg）, midazolam （0.05 mg/kg）, fentanyl （0. 005 mg/kg） and Norcuron （0.1 mg/kg ）were used during the induction of anaesthesia with the help of tracheal intubation; group 2： midazolam （0.05 mg/kg）, fentanyl （0.005 mg/kg） and Norcuron（0. 1 mg/kg） were used. HR, SBP and DBP, were monitored and recorded before the anesthesia induction and tracheal cannula. Result： The changes of Heart rates in group 1 was not significantly different （ P 〉 0.05 ） while in group 2 increased obviously （ P 〈 0.05 ）. The SBP in group 1 was dramatically increased（ P 〈 0.05 ） and the increase of DBP had no statistical significance （P 〉 0.05）. The SBP in group 2 decreased dramatically （ P 〈 0.05 ） and the decrease of DBP had no statistical significance （ P 〉 0.05 ）. Conclusion： Minor dose ketamine have good clinical effect for hemorrhagic shock patients caused by ruptured ectopic pregnancy under general anesthesia.