胃癌患者血清CA724、CA199、CEA检测的临床意义

目的探讨血清糖类抗原724(CA724)、糖类抗原199(CA199)、癌胚抗原(CEA)在胃癌诊断及与良性胃疾病鉴别诊断中的临床价值。方法用电化学发光免疫技术测定胃癌、胃炎、胃溃疡患者血清CA724、CA199、CEA。结果胃炎、胃溃疡患者血清CA724、CA199、CEA无统计学差异,良性胃疾病患者阳性率分别为26.4%、5.6%、12.5%;胃癌患者阳性率分别为50.0%、25.0%、33.3%,CA724、CEA两项联合检测阳性率为66.7%。结论血清CA724、CA199、CEA或CA724、CEA两项联合检测在胃癌诊断、良恶性胃疾病鉴别诊断中有一定价值。

Clinical significance of serum CA724,CA199 and CEA in patients with gastric Carcinoma

Objective To investigate the clinical value of the serum level of CA724,CA199 and CEA in the diagnosis of gastric carcinoma and its differential diagnosis with other benign gastric diseases.Methods The serum CA724,CA199 and CEA were detected in the patients with gastric carcinoma,gastritis and gastric ulcer by using electrochemiluminescence immunization technique.Results The serum level of CA724,CA199 and CEA had no statistical difference between gastritis and gastric ulcer.The positive rate of the above indexes was 26.4%,5.6% and 12.5% respectively in benign gastric diseases and 50.0%,25.0% and 33.3% respectively in gastric carcinoma.Furthermore,the positive rate of union detection of CA724 and CEA in gastric carcinoma was 66.7%.Conclusion The detection of the serum level of CA724,CA199 and CEA or union detection of CA724 and CEA are valuable to diagnose gastric carcinoma and identify the benign and malignant gastric diseases.