Evolución del leiomioma uterino después del tratamiento con mifepristona. Ensayo clínico aleatorizado |
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| Authors: | Josep L. Carbonell,Rita Acosta,Yasmiriam Pé rez,Marí a C. Yero,Isabel Seigler,Braulio Heredia |
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| Affiliation: | 1. Clínica Mediterránea Médica, Valencia, España;2. Departamento de Obstetricia/Ginecología, Hospital Docente Gineco-Obstétrico Eusebio Hernández, La Habana, Cuba;3. Departamento de Anatomopatología, Hospital Docente Gineco-Obstétrico Eusebio Hernández, La Habana, Cuba;4. Departamento de Ultrasonografía, Hospital Docente Gineco-Obstétrico Eusebio Hernández, La Habana, Cuba |
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| Abstract: | ObjectivesTo evaluate the extent in time of the reduction of uterine and fibroids size in women treated with mifepristone.Patients and methodsOne-hundred women who received mifepristone 10 or 5 mg for three months were followed-up for six months after treatment termination.ResultsSix months after treatment the fibroids mean sizes were 19% and 23% lower than baseline values in 10 and 5 mg mifepristone groups, respectively, and mean uterine volumes were 8% and 17% lesser than before treatment in 10 and 5 mg groups, respectively. Prevalence of symptoms was still significantly lower than before treatment.ConclusionsSix months after treatment termination the sizes of fibroids and uteri were near to the initial values but a clinical improvement was maintained. |
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| Keywords: | Mifepristona Mioma uterino Fibroma uterino |
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