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Antibiotic resistance pattern of enterotoxigenicEscherichia coli isolated from infants and young adults in Israel
Authors:D. Turner  N. Porat  D. Cohen  M. Yavzori  D. Fraser  N. Peled  O. Ohana  R. Dagan
Affiliation:(1) Pediatric Infectious Disease Unit, Soroka Medical Center, Faculty of Health Sciences, Ben-Gurion University of the Negev, PO Box 151, 84101 Beer Sheva, Israel;(2) Sackler School of Medicine, Tel Aviv University, Israel;(3) Israeli Defense Force, Medical Corps, Military Post, 02149, Israel;(4) Department of Epidemiology, Soroka Medical Center, Faculty of Health Sciences, Ben-Gurion University of the Negev, PO Box 151, 84101 Beer Sheva, Israel;(5) Clinical Microbiology Laboratory, Soroka Medical Center, Faculty of Health Sciences, Ben-Gurion University of the Negev, PO Box 151, 84101 Beer Sheva, Israel
Abstract:The aim of this study was to describe antibiotic resistance rates of enterotoxigenicEscherichia coli in Israel in order to facilitate the empirical choice of antibiotic treatment or prophylaxis for traveler's diarrhea and infantile diarrhea in our region. A total of 281 enterotoxigenicEscherichia coli isolates were tested: 144 from Bedouin infants and 137 from Israeli soldiers. Antibiotic-resistant isolates were prevalent in both groups, but higher resistance rates were found in the pediatric group. Strains producing heat-labile toxin showed higher resistance rates than strains producing heat-stable toxin. The results obtained in Israel preclude the use of many commonly used antibiotics for the treatment of traveler's diarrhea. Quinolones, however, are still effective.
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