石墨炉原子吸收光谱法测定中成药中重金属的含量

目的:测定中成药银丹心脑通胶囊、金莲花胶囊和七叶安神滴丸中重金属铅、砷、镉的含量。方法:采用石墨炉原子吸收光谱法,样品消化后直接进行测定。结果:重金属铅、砷、镉的进样浓度分别在3～18、20～80、0.2～1.2μg.L-1范围内与吸光度线性关系良好,r分别为0.9996、0.9999、0.9998;3种成分的回收率在95%～103%之间。结论:上述中成药中所含铅、砷、镉含量均符合规定;本法简单、快速、灵敏,适用于中成药中微量重金属的分析。

Content Determination of Heavy Metals in Chinese Patent Medicine by Graphite Furnace Atomic Absorption Spectrometry

OBJECTIVE： To determine the contents of lead, arsenic and cadmium in Chinese patent medicine Yindan Xinnaotong capsules, Jinlianhua capsules, Qiye anshen dripping pills. METHODS： After samples were directly digested, graphite furnace absorption spectrometry （GFAAS） was adopted for the determination of samples. RESULTS： The calibration curves were linear in the range of 3-18 μg·L^-1 for lead（r=0.999 6）,20-80μg·L^-1 for arsenic （r=0.999 9） ,0.2-1.2 μg·L^-1 for cadmium （r=0.999 8）. Average recovery rate were 95% -103% .CONCLUSION： The method is suitable for the determination of heavy metals in Chinese patent medicines with the advantages of being simple, rapid, sensitive.