| 胸上段食管癌调强放疗和三维适形放疗剂量学研究 |
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| 引用本文： | 葛小林,孙新臣,陈文湛,李益坤.胸上段食管癌调强放疗和三维适形放疗剂量学研究[J].中国医学物理学杂志,2010,27(2):1708-1711,1720. |
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| 作者姓名： | 葛小林 孙新臣 陈文湛 李益坤 |
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| 作者单位： | 东南大学附属中大医院肿瘤中心,江苏,南京,210009 |
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| 摘 要： | 目的:比较分析胸上段食管癌调强适形(IMRT)放疗和三维适形(3D-CRT)放疗的剂量学差异。方法:选择10例胸上段食管癌患者,应用三维治疗计划系统(TPS)分别为每例患者设计2种治疗计划(A:调强适形放疗;B:三维适形放疗),在规定PTV至少达到95%处方剂量前提下根据体积直方图(DVH)比较2种计划靶区剂量分布及脊髓、肺、心脏等正常组织受量的差异。结果:2种计划的靶区适形度指数(CI)、均匀性指数(HI)、处方剂量覆盖PTV百分比均以IM-RT计划为好,IMRT同时减少了脊髓最大所受剂量,差异均有统计学意义(P0.05);2种计划的双肺受照剂量V20、心脏平均剂量均在可耐受的范围内,差异无统计学意义(P0.05)。结论:胸上段食管癌采用IMRT优于3DCRT放疗,是目前较好的一种放疗方法。
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| 关 键 词： | 食管癌 三维适形放射治疗 调强适形放射治疗 剂量学 |
Dosimetry Study of IMRT and 3D-CRT Radiotherapies for Patients with Upper Esophageal Carcinoma |
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| GE Xiao-lin,SUN Xin-chen,CHEN Wen-zhang,LI Yi-kun.Dosimetry Study of IMRT and 3D-CRT Radiotherapies for Patients with Upper Esophageal Carcinoma[J].Chinese Journal of Medical Physics,2010,27(2):1708-1711,1720. |
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| Authors: | GE Xiao-lin SUN Xin-chen CHEN Wen-zhang LI Yi-kun |
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| Institution: | GE Xiao-lin,SUN Xin-chen,CHEN Wen-zhang,LI Yi-kun(Tumor Center of the Affiliated ZhongDa Hospital of Southeast University,Nanjing Jiangsu 210009,China) |
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| Abstract: | Objective:To compare the difference of intensity modulated radiation therapy( IMRT) ,3-D imensional conformal radiation therapy(3DCRT) for patients with upper esophageal carcinoma. Methods:Ten patients with upper esophageal carcinoma were treated by intensity modulated radiation therapy and 3-D imensional conformal radiation therapy at the same TPS,the difference of exposure dose between target area and critical organ was compared by dose volume histogram(DVH) with the plan target volume(PTV) must reach 95%... |
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| Keywords: | esophageal carcinoma 3-dimensional conformal radiation therapy intensiry modulated radiation therapy dosimetry |
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