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COPD 患者血清合肽素测定的临床意义
引用本文:胡昆,陆友金. COPD 患者血清合肽素测定的临床意义[J]. 临床肺科杂志, 2014, 19(1): 85-87
作者姓名:胡昆  陆友金
作者单位:胡昆 (合肥,安徽医科大学第二附属医院呼吸内科,安徽,230601); 陆友金 (合肥,安徽医科大学第二附属医院呼吸内科,安徽,230601);
摘    要:目的 探讨血清合肽素测定对于COPD患者的临床意义.方法 测定COPD患者治疗前后及对照组的血清合肽素(copeptin)、白介素-6(IL-6),比较二组相关数值的差异.结果 治疗前COPD患者的血清合肽素A组(0.94±0.17)ug/L明显高于B组(0.39±0.04)μg/L及对照组(0.07±0.03)μg/L,治疗后A组、B组COPD患者血清合肽素均较治疗前显著降低,分别为(0.17±0.03)和(0.11±0.03)μg/L.治疗后COPD患者血清IL-6与治疗前相比,明显下降.结论 COPD患者血清合肽素的检测可作为判断疗效的一项指标.

关 键 词:慢性阻塞性肺疾病  血清合肽素  酶联免疫吸附法

Clinical significance of serum copeptin in patients with COPD
HU Kun,LU You-jin. Clinical significance of serum copeptin in patients with COPD[J]. Journal of Clinical Pulmonary Medicine, 2014, 19(1): 85-87
Authors:HU Kun  LU You-jin
Affiliation:Department of Respira- tory Disease, the Second Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230601, China
Abstract:Objective To study the clinical significance of the detection of serum copeptin in patients with COPD. Methods The levels of serum c, opeptin and IL-6 were detected in COPD patients and healthy controls. Resuits The level of serum c, opeptin was the highest in the group A hefore the treatment. And the levels of serum copeptin and IL-6 decreased more obviously in COPD patients after the treatment than before. Conclusion The de- tection of serum cnpeptin can be used as an intlammatory marker for judging the curative effect in COPD patients.
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